Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Setd4tm2.1(cre/ERT2)Wjy
Name:	SET domain containing 4; targeted mutation 2.1, Wei-Jun Yang
MGI ID:	MGI:6822323
Synonyms:	SETD4-CreERT2
Gene:	Setd4  Location: Chr16:93380345-93400951 bp, - strand  Genetic Position: Chr16, 54.52 cM
Alliance:	Setd4tm2.1(cre/ERT2)Wjy page

Germline Transmission:	Earliest citation of germline transmission: J:314227
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Setd4tm2.1(cre/ERT2)Wjy expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Setd4 (MGI:2136890)   Mutation details: By homologous recombination in ES cells, a V5-P2A-CreERT2-WPRE-polyA cassette was inserted after the exon 12 of the mouse Setd4 gene. Resulted chimeras were crossed with Flp mice to remove the neo selection cassette. (J:314227)

Activity:	Tissue activity of this recombinase allele
Driver:	Setd4 (mouse) Summary of all recombinase alleles driven by Setd4. Comparative matrix view of recombinase activities Alliance mouse Setd4 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Setd4 Mutation:	28 strains or lines available

Original:	J:314227 Tian JZ, et al., SETD4-expressing cells contribute to pancreatic development and response to cerulein induced pancreatitis injury. Sci Rep. 2021 Jun 15;11(1):12614
All:	3 reference(s)