Gene Expression Data
Assay Details
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Assay
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Reference:
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J:88168
Hahm K, et al., Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1. Mol Cell Biol. 2004 Mar;24(5):2074-82
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6818646
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Gene symbol:
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Nefm
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Gene name:
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neurofilament, medium polypeptide
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Results
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Specimen
5A:
embryonic day 9.5
(more  )
Specimen
5A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5B:
embryonic day 9.5; Lmo4tm2Sho/Lmo4 +
(more )
Specimen
5B:
(close )
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Genetic Background:
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either: (involves: 129/Sv * CD-1) or (involves: 129/Sv * C57BL/6)
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Mutant Allele(s):
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Lmo4tm2Sho/Lmo4+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: nervous system |
Present |
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5B
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There is a fusion of cranial nerves IX and X in 25% of the embryos.
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Specimen
5C:
(close )
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Genetic Background:
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either: (involves: 129/Sv * CD-1) or (involves: 129/Sv * C57BL/6)
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Mutant Allele(s):
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Lmo4tm2Sho/Lmo4tm2Sho
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: nervous system |
Present |
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5C
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There is a fusion of cranial nerves IX and X in 50% of the mutants. There are defects in cranial nerve V in 20% of embryos examined.
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Specimen
5D:
(close )
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Genetic Background:
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either: (involves: 129/Sv * CD-1) or (involves: 129/Sv * C57BL/6)
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Mutant Allele(s):
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Lmo4tm2Sho/Lmo4tm2Sho
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: nervous system |
Present |
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5D
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There is a fusion of cranial nerves IX and X in 50% of the mutants. There are defects in cranial nerve V in 20% of embryos examined. The connection between ganglion and rhombomere 2 exit points are greatly reduced or missing in these embryos compared to wild-type.
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Analysis Tools
