Tg(Gsta1-NFE2L2/luc)M2Tiw
Transgene Detail
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| Symbol: |
Tg(Gsta1-NFE2L2/luc)M2Tiw |
| Name: |
transgene insertion M2, Takao Iwawaki |
| MGI ID: |
MGI:6791300 |
| Synonyms: |
OKD48, OKD48Luc, Tg(3xARE/TK-NRF2/luc)M2Tiw |
| Transgene: |
Tg(Gsta1-NFE2L2/luc)M2Tiw Location: unknown
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| Alliance: |
Tg(Gsta1-NFE2L2/luc)M2Tiw page
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| Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence, Reporter) |
| Inducer: |
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antioxidant |
| Mutation: |
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Insertion
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Tg(Gsta1-NFE2L2/luc)M2Tiw expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
NFE2L2 (4780) |
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Tg(Gsta1-NFE2L2/luc)M2Tiw expression driven by
1 gene
Transgene expression driven by:
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Mutation details: The transgene contains three copies of the antioxidant responsive element from the mouse Gsta1 promoter fused to a basal TK promoter driving inducible expression of human NRF2 (amino acids 1-433) with a FLAG-tagged luciferase reporter gene. Line M2 was generated.
(J:257947)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:257947 Oikawa D, et al., A transgenic mouse model for monitoring oxidative stress. Sci Rep. 2012;2:229 |
| All: |
6 reference(s) |
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Analysis Tools
