Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Zbtb7b/CD4-cre,-CD2)#Tani
Name:	transgene insertion, Ichiro Taniuchi
MGI ID:	MGI:6784021
Synonyms:	ThPOK-Cre
Transgene:	Tg(Zbtb7b/CD4-cre,-CD2)#Tani  Location: unknown
Alliance:	Tg(Zbtb7b/CD4-cre,-CD2)#Tani page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Epitope tag, Recombinase) Mutation:    Insertion   Tg(Zbtb7b/CD4-cre,-CD2)#Tani expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Zbtb7b (MGI:102755)   Mutation details: A 562base pair fragment of the Zbtb7b silencer sequence was inserted into a mini-transgene containing the minimal Cd4 enhancer-promoter-cre. The sequence encoding an internal ribosomal entry site and human CD2 were also inserted downstream of the cDNA cassette encoding Cre. The transgene expresses Cre specifically in the CD4 lineage. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:193392)

Activity:	Tissue activity of this recombinase allele
Driver:	Zbtb7b (mouse) Summary of all recombinase alleles driven by Zbtb7b. Alliance mouse Zbtb7b gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:193392 Mucida D, et al., Transcriptional reprogramming of mature CD4(+) helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes. Nat Immunol. 2013 Mar;14(3):281-9
All:	3 reference(s)