Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(CD68-MSR1)11Drg
Name:	transgene insertion 11, David Greaves
MGI ID:	MGI:6781268
Synonyms:	hSR-A III.1
Transgene:	Tg(CD68-MSR1)11Drg  Location: unknown
Alliance:	Tg(CD68-MSR1)11Drg page

Strain of Origin:

CBA x C57BL/6

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence, Modified isoform(s)) Mutation:    Insertion   Tg(CD68-MSR1)11Drg expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human MSR1 (4481) Msr1  (MGI:98257) "human promoter, human cDNA for type III isoform"   Mutation details: The transgene contains the following elements: the human CD68 promoter and intron 1, sequence coding for a FLAG tag, in-frame with the cDNA for human type III membrane-bound macrophage scavenger receptor 1 isoform, and bovine growth hormone poly(A) signal sequence. (J:132589)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:132589 Gough PJ, et al., The use of human CD68 transcriptional regulatory sequences to direct high-level expression of class A scavenger receptor in macrophages in vitro and in vivo. Immunology. 2001 Jul;103(3):351-61
All:	1 reference(s)