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Gene Expression Data
Assay Details
Assay
Reference: J:141111 Chang CP, et al., Pbx1 functions in distinct regulatory networks to pattern the great arteries and cardiac outflow tract. Development. 2008 Nov;135(21):3577-86
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6781265
Gene symbol: Pbx1
Gene name: pre B cell leukemia homeobox 1
Antibody: anti-Pbx1b
Results
Specimen 3A: embryonic day 8.75 (more )
Structure Level Pattern Image Note
TS14: future hindbrain neural crest Present 3A Expressed in all cells of the hindbrain, including the premigratory neural crest cells at the extreme dorsal tip of the neural tube (the neuroectodermal junction).
TS14: future hindbrain Present Widespread 3A
TS14: paraxial mesenchyme Present 3A

Specimen 3B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain neural fold Present 3B Expressed in many, but not all, cells of the neural tube, including the premigratory neural crest cells.
TS15: paraxial mesenchyme Present 3B

Specimen 3C: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: outflow tract Strong Regionally restricted 3C Expressed in vascular smooth muscle cells.
TS18: outflow tract endocardial cushion Weak Widespread 3C Expressed throughout the mesenchyme, most likely in cells derived from both endocardial cells (by an epithelial-to-mesenchymal transformation) and neural crest cells.
TS18: outflow tract cardiac muscle Present 3C Reduced expression.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory