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Gene Expression Data
Assay Details
Assay
Reference: J:141111 Chang CP, et al., Pbx1 functions in distinct regulatory networks to pattern the great arteries and cardiac outflow tract. Development. 2008 Nov;135(21):3577-86
Assay type: RNA in situ
MGI Accession ID: MGI:6781255
Gene symbol: Msx2
Gene name: msh homeobox 2
Probe: Msx2 probe8
Probe preparation: Antisense RNA
Results
Specimen 2I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present 2I
TS17: 2nd branchial arch mesenchyme Present 2I
TS17: 3rd branchial arch mesenchyme Present 2I
TS17: 4th branchial arch mesenchyme Present 2I
Specimen 2J: embryonic day 10.5; Pbx1tm1Mlc/Pbx1tm1Mlc (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present 2J
TS17: 2nd branchial arch mesenchyme Present 2J
TS17: 3rd branchial arch mesenchyme Present 2J
TS17: 4th branchial arch mesenchyme Present 2J The pharyngeal groove separating arch 3 and 4 was absent, and the fourth branchial arch was smaller than normal with reduced expression.
Specimen 6E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: rhombomere 5 Strong 6E
TS15: rhombomere 6 Present 6E Expressed in lower levels.
TS15: rhombomere 7 Present 6E Expressed in lower levels.
TS15: rhombomere 8 Present 6E Expressed in lower levels.
Specimen 6F: embryonic day 9.5; Pbx1tm1Mlc/Pbx1tm1Mlc (more )
Structure Level Pattern Image Note
TS15: rhombomere 5 Strong 6F
TS15: rhombomere 6 Present 6F Considerably higher expression compared with the wild-type.
TS15: rhombomere 7 Present 6F Considerably higher expression compared with the wild-type.
TS15: rhombomere 8 Present 6F Considerably higher expression compared with the wild-type.
Specimen 6G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: rhombomere 6 Present 6G
Specimen 6H: embryonic day 9.5; Pbx1tm1Mlc/Pbx1tm1Mlc (more )
Structure Level Pattern Image Note
TS15: rhombomere 6 Present 6H Enhanced expression in the dorsal neural tube compared with the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory