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Gene Expression Data
Assay Details
Assay
Reference: J:196769 Ramachandran A, et al., Localization of transforming growth factor beta receptor II interacting protein-1 in bone and teeth: implications in matrix mineralization. J Histochem Cytochem. 2012 Apr;60(4):323-37
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6781217
Gene symbol: Eif3i
Gene name: eukaryotic translation initiation factor 3, subunit I
Antibody: anti-Eif3b (sc-271539)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cervical vertebral cartilage condensation Present Regionally restricted 1A Expression is in the chondrocytes of the cartilaginous primordium of the basioccipital bone in the rostral part of the vertebral column with the forming cervical vertebrae.
TS21: intervertebral disc Absent 1A

Specimen 1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw tooth Present 1B , S1
TS21: oral epithelium Present Regionally restricted 1B , S1 Expression is in the invaginating epithelium.
TS21: lower jaw tooth mesenchyme Present Regionally restricted 1B , S1 Expression is in the condensing mesenchyme, the dental papilla.

Specimen 1C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: Meckel's cartilage Present Regionally restricted 1C Expression is in chondrocytes.
TS24: basement membrane Present 1D , 1C
TS24: mandible Present Regionally restricted 1D , 1C Expression is in the osteoblasts and alveolar bone matrix of the alveolar bone.
TS24: lower jaw incisor Present Regionally restricted 1D , 1C Expression is in dental pulp cells and in the stem cell niche of the cervical loop at the apical end.

Specimen 2A: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: molar dental papilla Weak Regionally restricted 2A Expression is in odontoblasts.
TS27: molar enamel organ Weak Regionally restricted 2A Expression is in ameloblasts.

Specimen 2B: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: basement membrane Present Regionally restricted 2B Expression is in the basement membrane of the incisors.
TS27: incisor dental papilla Present Regionally restricted 2B Expression is in odontoblasts.

Specimen 2C: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: alveolar process Present 2C
TS27: molar dental papilla Present Regionally restricted 2C Expression is in odontoblasts.
TS27: molar enamel organ Present Regionally restricted 2C Expression is in ameloblasts.

Specimen 2D: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: extracellular matrix Present 2D
TS27: incisor dental papilla Present Regionally restricted 2D Expression is in odontoblasts.
TS27: incisor Present Regionally restricted 2D Expression is at the mineralization front during the assembly of the calcified dentin matrix.

Specimen 2E: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: molar Present 2E
TS28: molar dental papilla Present Regionally restricted 2E Expression is in odontoblasts.

Specimen 2F: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: incisor Present 2F
TS28: incisor dental papilla Present Regionally restricted 2F Expression is in odontoblasts.

Specimen 2G: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: dentin Strong 2G
TS28: extracellular matrix Present 2G
TS28: molar Present 2G
TS28: molar dental papilla Present Regionally restricted 2G Expression is in odontoblasts.

Specimen 2H: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: incisor Present 2H
TS28: incisor dental papilla Present Regionally restricted 2H Expression is in odontoblasts.

Specimen 3A: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: alveolar process Present 3B , 3A
TS28: dental pulp Present 3B , 3A
TS28: dentin Present 3B , 3A
TS28: extracellular matrix Present 3B , 3A
TS28: lower jaw molar Present 3B , 3A
TS28: lower jaw incisor dental papilla Present Regionally restricted 3A , 3B Expression is in odontoblasts.
TS28: lower jaw molar dental papilla Present Regionally restricted 3A , 3B Expression is in odontoblasts.

Specimen 3C: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: extracellular matrix Present 3D , 3C
TS28: lower jaw molar Present 3D , 3C
TS28: mandible Present 3D , 3C
TS28: lower jaw incisor dental papilla Present Regionally restricted 3C , 3D Expression is in odontoblasts.
TS28: lower jaw molar dental papilla Present Regionally restricted 3C , 3D Expression is in odontoblasts.
TS28: alveolar process Present Regionally restricted 3D , 3C Expression is in osteoblasts.

Specimen 4A: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: femur Present Regionally restricted 4A Expression is in the growth plate region in the nuclei of chondrocytes and is absent in the hypertrophic chondrocytes of the growth plate.
TS27: extracellular matrix Present Regionally restricted 4A Expression is in the extracellular matrix of the proliferating chondrocytes.

Specimen 4B: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: femur Present Regionally restricted 4B Expression is in the growth plate region in the nuclei of chondrocytes.
TS27: extracellular matrix Present Regionally restricted 4B Expression is in the extracellular matrix of the proliferating chondrocytes.

Specimen 4C: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: femur Present Regionally restricted 4C Expression is in the growth plate region in the nuclei of chondrocytes.
TS28: extracellular matrix Present Regionally restricted 4C Expression is in prehypertrophic extracellular matrix.
TS28: periosteum Present 4C

Specimen 4D: postnatal week 4 (more )
Structure Level Pattern Image Note
TS28: femur Present Regionally restricted 4D Expression is in the growth plate region in the nuclei of chondrocytes and is absent in the proliferating cells and in the cartilage matrix.
TS28: extracellular matrix Present 4D

Specimen 5A: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: periosteum Present 5B , 5A
TS27: long bone Present Regionally restricted 5A , 5B Expression is in pre-osteoblasts.

Specimen 5C: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: periosteum Present 5C , 5D
TS27: long bone Present Regionally restricted 5C , 5D Expression is in pre-osteoblasts.

Specimen 6A: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: extracellular matrix Present 6A , 6B
TS28: periosteum Present 6A , 6B
TS28: long bone Present Regionally restricted 6B , 6A Expression is in the mineralizing matrix and in osteocytes and osteoblasts.

Specimen 6B inset: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: periosteum Present 6B inset

Specimen 6C: postnatal week 4 (more )
Structure Level Pattern Image Note
TS28: extracellular matrix Present 6C , 6D
TS28: periosteum Present 6C , 6D
TS28: long bone Present Regionally restricted 6C , 6D Expression is osteocytes and osteoblasts, bone spicules of the primary spongiosa, and mineralized matrix of cortical bone.

Specimen S3C: postnatal week 4 (more )
Structure Level Pattern Image Note
TS28: long bone Present Regionally restricted S3C Expression is osteocytes and osteoblasts, bone spicules of the primary spongiosa, and mineralized matrix of cortical bone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory