Gene Expression Data
Assay Details
Assay
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Reference:
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J:63996
Ringvall M, et al., Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/N-sulfotransferase-1. J Biol Chem. 2000 Aug 25;275(34):25926-30
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6780765
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Gene symbol:
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Sftpb
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Gene name:
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surfactant associated protein B
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Antibody:
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anti-Surfactant B
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Detection system:
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Secondary antibody coupled to fluorescein
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Assay notes:
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These data are described in the text.
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Results
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Specimen
WT:
embryonic day 18.5
(more )
Specimen
WT:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS26: lung |
Present |
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|
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Specimen
-/-:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Ndst1tm1Ekf/Ndst1tm1Ekf
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS26: lung |
Present |
|
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The authors state that this mutant appears to have less secreted surfactant but an increased number of the cells producing these proteins.
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