Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(CD68-Edil3)#Chav
Name:	transgene insertion, Triantafyllos Chavakis
MGI ID:	MGI:6780171
Synonyms:	CD68-Del1
Transgene:	Tg(CD68-Edil3)#Chav  Location: unknown
Alliance:	Tg(CD68-Edil3)#Chav page

Strain of Origin:

C57BL/6NCrl

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(CD68-Edil3)#Chav expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Edil3 (MGI:1329025) "human promoter, mouse cDNA"   Mutation details: The transgene contains the following elements: the human CD68 promoter and intron 1, murine EGF-like repeats and discoidin I-like domains 3 cDNA, and poly(A) signal sequences of unstated origin. This allele drives Edil3 expression in macrophages. (J:282521)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:282521 Kourtzelis I, et al., DEL-1 promotes macrophage efferocytosis and clearance of inflammation. Nat Immunol. 2019 Jan;20(1):40-49
All:	2 reference(s)