Tg(CD68-Edil3*)#Chav
Transgene Detail
|
|
| Symbol: |
Tg(CD68-Edil3*)#Chav |
| Name: |
transgene insertion, Triantafyllos Chavakis |
| MGI ID: |
MGI:6780174 |
| Synonyms: |
CD68-Del1-[E1-E3] |
| Transgene: |
Tg(CD68-Edil3*)#Chav Location: unknown
|
| Alliance: |
Tg(CD68-Edil3*)#Chav page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(CD68-Edil3*)#Chav expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Edil3 (MGI:1329025) |
"human promoter, truncated mouse cDNA" |
|
| |
|
Mutation details: The transgene contains the following elements: the human CD68 promoter and intron 1, murine EGF-like repeats and discoidin I-like domains 3 cDNA lacking sequence coding for the discoidin I-like domains, and poly(A) signal sequences of unstated origin. This allele drives expression of truncated Edil3 in macrophages.
(J:282521)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:282521 Kourtzelis I, et al., DEL-1 promotes macrophage efferocytosis and clearance of inflammation. Nat Immunol. 2019 Jan;20(1):40-49 |
| All: |
1 reference(s) |
|
Analysis Tools
