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Gene Expression Data
Assay Details
Assay
Reference: J:309563 Rafipay A, et al., Knockdown of slit signaling during limb development leads to a reduction in humerus length. Dev Dyn. 2021 Sep;250(9):1340-1357
Assay type: RNA in situ
MGI Accession ID: MGI:6780206
Gene symbol: Gdf5
Gene name: growth differentiation factor 5
Probe: Gdf5 probe15
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2C Gdf5 Slit1+/+: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: carpal-metacarpal joint Present 2C Gdf5 Slit1+/+
TS23: metacarpal-phalangeal joint Present 2C Gdf5 Slit1+/+
TS23: forelimb interphalangeal joint Present Regionally restricted 2C Gdf5 Slit1+/+ Expression in proximal and distal interphalangeal joints
Specimen 2C Gdf5 Slit1-/- Slit2-/-: embryonic day 15.5; Slit1tm1.1Matl/Slit1tm1.1Matl, Slit2tm1Matl/Slit2tm1Matl (more )
Structure Level Pattern Image Note
TS23: carpal-metacarpal joint Present 2C Gdf5 Slit1-/- Slit2-/-
TS23: metacarpal-phalangeal joint Present 2C Gdf5 Slit1-/- Slit2-/-
TS23: forelimb interphalangeal joint Present Regionally restricted 2C Gdf5 Slit1-/- Slit2-/- Expression in proximal and distal interphalangeal joints
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory