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Gene Expression Data
Assay Details
Assay
Reference: J:310126 Quarta C, et al., Functional identity of hypothalamic melanocortin neurons depends on Tbx3. Nat Metab. 2019 Feb;1(2):222-235
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6766567
Gene symbol: Tbx3
Gene name: T-box 3
Antibody: anti-Tbx3 (A303-098A)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen S1f - ACR: postnatal week 12; Tbx3em1(cre)Mhts/Tbx3+ (more )
Note: Double labeled: red - Tbx3 protein; green - Tbx3 reporter (assay MGI:6764615).
Structure Level Pattern Image Note
TS28: arcuate nucleus Present Regionally restricted S1f ARC Expression is seen in neurons.
Specimen S1f - NTS: postnatal week 12; Tbx3em1(cre)Mhts/Tbx3+ (more )
Note: Double labeled: red - Tbx3 protein; green - Tbx3 reporter (assay MGI:6764615).
Structure Level Pattern Image Note
TS28: solitary tract nucleus Present Regionally restricted S1f NTS Expression is seen in neurons.
Specimen S2g - control: postnatal week 12; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Pomc1-cre)16Lowl/0 (more )
Note: Conditional mutant. Double labeled: magenta - Tbx3; green - Cre reporter.
Structure Level Pattern Image Note
TS28: arcuate nucleus Present S2g left
Specimen S2g - mutant: postnatal week 12; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tbx3tm3.1Moon/Tbx3tm3.1Moon, Tg(Pomc1-cre)16Lowl/0 (more )
Note: Conditional mutant. Double labeled: magenta - Tbx3; green - Cre reporter.
Structure Level Pattern Image Note
TS28: arcuate nucleus Present S2g right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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