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Gene Expression Data
Assay Details
Assay
Reference: J:201922 Kim GW, et al., Mice lacking alpha-tubulin acetyltransferase 1 are viable but display alpha-tubulin acetylation deficiency and dentate gyrus distortion. J Biol Chem. 2013 Jul 12;288(28):20334-50
Assay type: Western blot
MGI Accession ID: MGI:6766374
Gene symbol: Tuba1a
Gene name: tubulin, alpha 1A
Antibody: anti-acetylated alpha-tubulin 6-11b-1 (T7451)
Detection system: horseradish peroxidase
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
Testis +/+ P adult TS28: testis Present involves: C57BL/6 * C57BL/6NTac Male
Testis -/- P adult TS28: testis Absent (a) involves: C57BL/6 * C57BL/6NTac Atat1tm1(KOMP)Vlcg/Atat1tm1(KOMP)VlcgMale
Kidney +/+ P adult TS28: metanephros Present involves: C57BL/6 * C57BL/6NTac Not Specified
Kidney -/- P adult TS28: metanephros Absent (a) involves: C57BL/6 * C57BL/6NTac Atat1tm1(KOMP)Vlcg/Atat1tm1(KOMP)VlcgNot Specified
Liver +/+ P adult TS28: liver Present involves: C57BL/6 * C57BL/6NTac Not Specified
Liver -/- P adult TS28: liver Absent (a) involves: C57BL/6 * C57BL/6NTac Atat1tm1(KOMP)Vlcg/Atat1tm1(KOMP)VlcgNot Specified
Lung +/+ P adult TS28: lung Present involves: C57BL/6 * C57BL/6NTac Not Specified
Lung -/- P adult TS28: lung Weak (b) involves: C57BL/6 * C57BL/6NTac Atat1tm1(KOMP)Vlcg/Atat1tm1(KOMP)VlcgNot Specified
Spleen +/+ P adult TS28: spleen Present involves: C57BL/6 * C57BL/6NTac Not Specified
Spleen -/- P adult TS28: spleen Weak (b) involves: C57BL/6 * C57BL/6NTac Atat1tm1(KOMP)Vlcg/Atat1tm1(KOMP)VlcgNot Specified
Fat +/+ P adult TS28: adipose tissue Present involves: C57BL/6 * C57BL/6NTac Not Specified
Fat -/- P adult TS28: adipose tissue Present (c) involves: C57BL/6 * C57BL/6NTac Atat1tm1(KOMP)Vlcg/Atat1tm1(KOMP)VlcgNot Specified
Brain +/+ P adult TS28: brain Strong (d) involves: C57BL/6 * C57BL/6NTac Not Specified
Brain -/- P adult TS28: brain Absent (a) involves: C57BL/6 * C57BL/6NTac Atat1tm1(KOMP)Vlcg/Atat1tm1(KOMP)VlcgNot Specified
Notes:
(a) Expression totally ablated.
(b) Acetylation dramatically or significantly decreased.
(c) Acetylation only minimally affected.
(d) Acetylation was highest in brain.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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