Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Cadps2tm1.1Ksak
Name:	Ca2+-dependent activator protein for secretion 2; targeted mutation 1.1, Kenji Sakimura
MGI ID:	MGI:6764588
Synonyms:	Caps2-flox
Gene:	Cadps2  Location: Chr6:23262772-23839420 bp, - strand  Genetic Position: Chr6, 10.57 cM
Alliance:	Cadps2tm1.1Ksak page

Germline Transmission:	Earliest citation of germline transmission: J:310161
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: Two loxP sites were inserted to flank exon 6 of the mouse Oxt gene. Frt flanked neo cassette was removed by crossing with the Actb-FLPe mouse line that expresses a Flp1 recombinase gene under the human ACTB promoter. (J:310161)

In Mice Carrying this Mutation:

10 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cadps2 Mutation:	86 strains or lines available

Original:	J:310161 Fujima S, et al., CAPS2 Deficiency Impairs the Release of the Social Peptide Oxytocin, as Well as Oxytocin-Associated Social Behavior. J Neurosci. 2021 May 19;41(20):4524-4535
All:	1 reference(s)