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Gene Expression Data
Assay Details
Assay
Reference: J:309394 Kwon HJ, et al., Hippo pathway/Yap regulates primary enamel knot and dental cusp patterning in tooth morphogenesis. Cell Tissue Res. 2015 Nov;362(2):447-51
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6764472
Gene symbol: Yap1
Gene name: yes-associated protein 1
Antibody: anti-P-Yap
Results
Specimen 1j: embryonic day 13.5 (more )
Note: Double labeled: green - phosphorylated Yap1; red - TOPRO-3.
Structure Level Pattern Image Note
TS21: tooth bud Present Regionally restricted 1j At bud stage; expression in basal cell layer of dental epithelium.
TS21: tooth epithelium Present Regionally restricted 1j At bud stage; expression in basal cell layer of dental epithelium.
Specimen 1k: embryonic day 14.5 (more )
Note: Double labeled: green - phosphorylated Yap1; red - TOPRO-3.
Structure Level Pattern Image Note
TS22: cap stage tooth Present Regionally restricted 1k At cap stage, expression in pattern similar to that of Ki67.
Specimen 1k': embryonic day 14.5 (more )
Note: Double labeled: green - phosphorylated Yap1; red - TOPRO-3.
Structure Level Pattern Image Note
TS22: primary enamel knot Present Regionally restricted 1k' In primary enamel knot (PEK), expression localized in cytoplasm.
Specimen 1l: embryonic day 16.5 (more )
Note: Double labeled: green - phosphorylated Yap1; red - TOPRO-3.
Structure Level Pattern Image Note
TS24: bell stage tooth Present Regionally restricted 1l At bell stage, authors report expression profile similar to those in primary enamel knot at cap stage.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory