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Gene Expression Data
Assay Details
Assay
Reference: J:309394 Kwon HJ, et al., Hippo pathway/Yap regulates primary enamel knot and dental cusp patterning in tooth morphogenesis. Cell Tissue Res. 2015 Nov;362(2):447-51
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6764470
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67
Results
Specimen 1d: embryonic day 13.5 (more )
Note: Double labeled: green - Mki67; red - TOPRO-3.
Structure Level Pattern Image Note
TS21: tooth bud Present Regionally restricted 1d At bud stage; expression in proliferating cells in basal cell layer of dental epithelium.
TS21: tooth epithelium Present Regionally restricted 1d At bud stage; expression in proliferating cells in basal cell layer of dental epithelium.
Specimen 1e: embryonic day 14.5 (more )
Note: Double labeled: green - Mki67; red - TOPRO-3.
Structure Level Pattern Image Note
TS22: cap stage tooth Present Regionally restricted 1e At cap stage, expression generally detected in tooth germ.
TS22: primary enamel knot Absent 1e
Specimen 1f: embryonic day 16.5 (more )
Note: Double labeled: green - Mki67; red - TOPRO-3.
Structure Level Pattern Image Note
TS24: bell stage tooth Present Regionally restricted 1f At bell stage, authors report expression profile similar to those in primary enamel knot at cap stage.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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