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Tg(Myh6-ESRRG)L10Javi
Transgene Detail
Summary
Symbol: Tg(Myh6-ESRRG)L10Javi
Name: transgene insertion L10, Josep A Villena
MGI ID: MGI:6763952
Synonyms: L10 hERR-Tg
Transgene: Tg(Myh6-ESRRG)L10Javi  Location: unknown  
Alliance: Tg(Myh6-ESRRG)L10Javi page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Epitope tag, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-ESRRG)L10Javi expresses 1 gene
 
Mutation detailsThis transgene consists of the alpha-myosin heavy chain promoter driving the expression of the human ERRG (hERRgamma) containing two Flag epitopes in the 5' region. Four founder lines L3, L6, L7, and L10 with varying expression levels and specific were established. L10 line exhibited preferential expression of the transgene in the heart but detectable expression in almost all other tissues analyzed. (J:310470)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:310470 Lasheras J, et al., Cardiac-Specific Overexpression of ERRgamma in Mice Induces Severe Heart Dysfunction and Early Lethality. Int J Mol Sci. 2021 Jul 28;22(15)
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory