Dnah11 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:286656 Shylo NA, et al., Loss of ciliary transition zone protein TMEM107 leads to heterotaxy in mice. Dev Biol. 2020 Apr 15;460(2):187-199
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:6763238
Gene symbol:	Dnah11
Gene name:	dynein, axonemal, heavy chain 11

Reporter:	GFP
Antibody:	anti-GFP (ab13970)
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

3K ©

3O ©

Specimen 3K/O: embryonic day 8.0; Dnah11^tm1.1Bknr/Dnah11^tm1.1Bknr (more

)
Note: Double labeled: green - Dnah11; red - Arl13b (assay MGI:6763183).

Structure	Level	Pattern	Image	Note
TS12: node	Present	Regionally restricted	3O , 3K	Expressed in all cilia in the pit.

3L ©

3P ©

Specimen 3L/P: embryonic day 8.0; Dnah11^tm1.1Bknr/Dnah11^tm1.1Bknr, Tmem107^tm1Lex/Tmem107^tm1Lex (more

)
Note: Double labeled: green - Dnah11; red - Arl13b (assay MGI:6763183).

Structure	Level	Pattern	Image	Note
TS12: node	Present	Regionally restricted	3L , 3P	Coexpressed with Arl13b in the much fewer cilia in the pit in the mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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