Dnah11 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:286656 Shylo NA, et al., Loss of ciliary transition zone protein TMEM107 leads to heterotaxy in mice. Dev Biol. 2020 Apr 15;460(2):187-199
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:6763238
Gene symbol:	Dnah11
Gene name:	dynein, axonemal, heavy chain 11

Reporter:	GFP
Antibody:	anti-GFP (ab13970)
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

3K ©

3O ©

Specimen 3K/O: embryonic day 8.0; Dnah11^tm1.1Bknr/Dnah11^tm1.1Bknr (more

)
Note: Double labeled: green - Dnah11; red - Arl13b (assay MGI:6763183).

Structure	Level	Pattern	Image	Note
TS12: node	Present	Regionally restricted	3O , 3K	Expressed in all cilia in the pit.

3L ©

3P ©

Specimen 3L/P: embryonic day 8.0; Dnah11^tm1.1Bknr/Dnah11^tm1.1Bknr, Tmem107^tm1Lex/Tmem107^tm1Lex (more

)
Note: Double labeled: green - Dnah11; red - Arl13b (assay MGI:6763183).

Structure	Level	Pattern	Image	Note
TS12: node	Present	Regionally restricted	3L , 3P	Coexpressed with Arl13b in the much fewer cilia in the pit in the mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24