Slc17a6tm1.1(icre/ERT2)Bcgen
Targeted Allele Detail
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Symbol: |
Slc17a6tm1.1(icre/ERT2)Bcgen |
Name: |
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 1.1, Biocytogen LLC |
MGI ID: |
MGI:6761378 |
Synonyms: |
vGLUT2-iCreERT2 |
Gene: |
Slc17a6 Location: Chr7:51271754-51320867 bp, + strand Genetic Position: Chr7, 32.78 cM, cytoband B4
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Alliance: |
Slc17a6tm1.1(icre/ERT2)Bcgen page
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Germline Transmission: |
Earliest citation of germline transmission:
J:243876
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Slc17a6tm1.1(icre/ERT2)Bcgen expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A 2A-icre/ERT2 is introduced between the coding sequence of Slc17a6 Exon 12 and 3' UTR. Neo cassette flanked by frt sites was inserted within intron 11 to avoid disrupting poly(A) signal of Slc17a6. After homologous recombination in ES cells, the neo selection cassette was removed by Flp recombinase.
(J:243876)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Slc17a6
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Slc17a6 Mutation: |
59 strains or lines available
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Original: |
J:243876 Zhong H, et al., Endocannabinoid signaling in hypothalamic circuits regulates arousal from general anesthesia in mice. J Clin Invest. 2017 Jun 01;127(6):2295-2309 |
All: |
1 reference(s) |
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