Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Lect2em1(cre)Smoc
Name:	leukocyte cell-derived chemotaxin 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:6760622
Synonyms:	Lect2-Cre, Lect2em1(2A-cre)Smoc
Gene:	Lect2  Location: Chr13:56690277-56696315 bp, - strand  Genetic Position: Chr13, 30.08 cM
Alliance:	Lect2em1(cre)Smoc page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Lect2em1(cre)Smoc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Lect2 (MGI:1278342)   Mutation details: A 2A-Cre expression cassette was knocked into the Lect2 gene stop codon site via CRISPR/Cas mediated recombination. (J:284498)

Activity:	Tissue activity of this recombinase allele
Driver:	Lect2 (mouse) Summary of all recombinase alleles driven by Lect2. Comparative matrix view of recombinase activities Alliance mouse Lect2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lect2 Mutation:	12 strains or lines available

Original:	J:284498 Xu M, et al., LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis. Cell. 2019 Sep 5;178(6):1478-1492.e20
All:	1 reference(s)