Tg(Asic1-cre)1Cibms
Transgene Detail
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Symbol: |
Tg(Asic1-cre)1Cibms |
Name: |
transgene insertion 1, Chih-Cheng Chen |
MGI ID: |
MGI:6759763 |
Synonyms: |
Asic1bCre, ASIC1b-Cre |
Transgene: |
Tg(Asic1-cre)1Cibms Location: unknown
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Alliance: |
Tg(Asic1-cre)1Cibms page
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Asic1-cre)1Cibms expression driven by
1 gene
Transgene expression driven by:
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Mutation details: The transgene consists of a ~4.5-kb mouse genomic DNA fragment containing the promoter upstream of the ATG translation start codon of a splicing variant of Asic1, ASIC1b to drive the Cre recombinase expression. The whole ASIC1b-CreDNA cassette was flanked by the chicken hypersensitive site 4 (HS4) insulator. Five founder mice were retained for copy number verification and two founder lines bearing a minimum copy transgene were screened. One of the five founder mice showing expression of Cre only in the trigeminal ganglia and DRG but not the brain was used for the study.
(J:309655)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Asic1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:309655 Chang CT, et al., Involvement of Acid-Sensing Ion Channel 1b in the Development of Acid-Induced Chronic Muscle Pain. Front Neurosci. 2019;13:1247 |
All: |
1 reference(s) |
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