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Tg(Asic1-cre)1Cibms
Transgene Detail
Summary
Symbol: Tg(Asic1-cre)1Cibms
Name: transgene insertion 1, Chih-Cheng Chen
MGI ID: MGI:6759763
Synonyms: Asic1bCre, ASIC1b-Cre
Transgene: Tg(Asic1-cre)1Cibms  Location: unknown  
Alliance: Tg(Asic1-cre)1Cibms page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Asic1-cre)1Cibms expression driven by 1 gene
 
Mutation detailsThe transgene consists of a ~4.5-kb mouse genomic DNA fragment containing the promoter upstream of the ATG translation start codon of a splicing variant of Asic1, ASIC1b to drive the Cre recombinase expression. The whole ASIC1b-CreDNA cassette was flanked by the chicken hypersensitive site 4 (HS4) insulator. Five founder mice were retained for copy number verification and two founder lines bearing a minimum copy transgene were screened. One of the five founder mice showing expression of Cre only in the trigeminal ganglia and DRG but not the brain was used for the study. (J:309655)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Asic1 (mouse)
Summary of all recombinase alleles driven by Asic1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:309655 Chang CT, et al., Involvement of Acid-Sensing Ion Channel 1b in the Development of Acid-Induced Chronic Muscle Pain. Front Neurosci. 2019;13:1247
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory