Tg(Hbb/Hoxa2-cre)2Fmr
Transgene Detail
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Symbol: |
Tg(Hbb/Hoxa2-cre)2Fmr |
Name: |
transgene insertion 2, Filippo M Rijli |
MGI ID: |
MGI:6759010 |
Synonyms: |
r2::Cre |
Transgene: |
Tg(Hbb/Hoxa2-cre)2Fmr Location: unknown
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Alliance: |
Tg(Hbb/Hoxa2-cre)2Fmr page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Hbb/Hoxa2-cre)2Fmr expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Hoxa2 (MGI:96174) |
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Mutation details: This transgene contains the beta-globin promoter fragment fused to the 2.5 kb mouse Hoxa2 rhombomere 2-specific enhancer element to drive expression of cre in rhombomere 2. This transgene allele was made with the same construct used for the generation of Tg(Hbb/Hoxa2-cre)1Fmr. Two new founders were generated and selected to have a similar rhombomere 2-specific expression pattern as the previous transgenic line. One founder was used for the study.
(J:309626)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Hoxa2
(mouse)
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User Notes:
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Additional information submitted by the research community
Additional information submitted by the research community
The creator of this transgene line states that cre expression was progressively lost after many generations of crossings of a previous line. (J:309626)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:309626 Bechara A, et al., Hoxa2 Selects Barrelette Neuron Identity and Connectivity in the Mouse Somatosensory Brainstem. Cell Rep. 2015 Oct 27;13(4):783-797 |
All: |
1 reference(s) |
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