Cntn1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:242541 Bizzoca A, et al., The gene encoding the mouse contactin-1 axonal glycoprotein is regulated by the collier/Olf1/EBF family early B-Cell factor 2 transcription factor. Dev Neurobiol. 2015 Dec;75(12):1420-40
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6758194
Gene symbol:	Cntn1
Gene name:	contactin 1

Antibody:	anti-Contactin-1
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase

Results

Specimen 1Aa: embryonic day 14.0 (more

)

Structure	Level	Pattern	Image	Note
TS22: cerebellum	Present	Regionally restricted	1Aa	Expression is in a cluster in the region of the nuclear transitory zone. Expression is weak and diffuse in the cerebellar plate and is absent in external granule cell layer.
TS22: cerebellar peduncle	Present		1Aa

Specimen 1Ab: embryonic day 14.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS22: cerebellum	Weak	Regionally restricted	1Ab	Expression is in a cluster in the region of the nuclear transitory zone. Expression is weak and diffuse in the cerebellar plate and is absent in external granule cell layer.
TS22: cerebellar peduncle	Weak		1Ab

Specimen 1Ac: embryonic day 14.0 (more

)

Structure	Level	Pattern	Image	Note
TS22: cerebellum	Present	Regionally restricted	1Ac	Expression is in a cluster in the region of the nuclear transitory zone. Expression is weak and diffuse in the cerebellar plate and is absent in external granule cell layer.
TS22: cerebellar peduncle	Present		1Ac

Specimen 1Ad: embryonic day 14.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS22: cerebellum	Weak	Regionally restricted	1Ad	Expression is in a cluster in the region of the nuclear transitory zone. Expression is weak and diffuse in the cerebellar plate and is absent in external granule cell layer.
TS22: cerebellar peduncle	Weak		1Ad

Specimen 1Ae: embryonic day 14.0 (more

)

Structure	Level	Pattern	Image	Note
TS22: cerebellum	Present	Regionally restricted	1Ae	Expression is in a cluster in the region of the nuclear transitory zone. Expression is weak and diffuse in the cerebellar plate and is absent in external granule cell layer.
TS22: cerebellar peduncle	Present		1Ae

Specimen 1Af: embryonic day 14.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS22: cerebellum	Weak	Regionally restricted	1Af	Expression is in a cluster in the region of the nuclear transitory zone. Expression is weak and diffuse in the cerebellar plate and is absent in external granule cell layer.
TS22: cerebellar peduncle	Weak		1Af

Specimen 1Ba: embryonic day 16.0 (more

)

Structure	Level	Pattern	Image	Note
TS24: cerebellum	Present	Regionally restricted	1Ba	Expression is in a cluster in the region of the nuclear transitory zone. There is diffuse expression in the posterior region of the folium on presumptive Purkinje cell precursors.
TS24: cerebellar peduncle	Present		1Ba
TS24: cerebellum external granule cell layer	Absent		1Ba

Specimen 1Bb: embryonic day 16.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS24: cerebellum	Trace	Regionally restricted	1Bb	Expression is in a cluster in the region of the nuclear transitory zone. There is diffuse expression in the posterior region of the folium on presumptive Purkinje cell precursors.
TS24: cerebellar peduncle	Trace		1Bb
TS24: cerebellum external granule cell layer	Absent		1Bb

Specimen 1Bc: embryonic day 16.0 (more

)

Structure	Level	Pattern	Image	Note
TS24: cerebellum	Present	Regionally restricted	1Bc	Expression is in a cluster in the region of the nuclear transitory zone. There is diffuse expression in the posterior region of the folium on presumptive Purkinje cell precursors.
TS24: cerebellar peduncle	Present		1Bc
TS24: cerebellum external granule cell layer	Absent		1Bc

Specimen 1Bd: embryonic day 16.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS24: cerebellum	Trace	Regionally restricted	1Bd	Expression is in a cluster in the region of the nuclear transitory zone. There is diffuse expression in the posterior region of the folium on presumptive Purkinje cell precursors.
TS24: cerebellar peduncle	Trace		1Bd	Expression is in a cluster in the region of the nuclear transitory zone. There is diffuse expression in the posterior region of the folium on presumptive Purkinje cell precursors.
TS24: cerebellum external granule cell layer	Absent		1Bd

Specimen 1Be: embryonic day 16.0 (more

)

Structure	Level	Pattern	Image	Note
TS24: cerebellum	Present	Regionally restricted	1Be	Expression is in a cluster in the region of the nuclear transitory zone. There is diffuse expression in the posterior region of the folium on presumptive Purkinje cell precursors.
TS24: cerebellar peduncle	Present		1Be
TS24: cerebellum external granule cell layer	Absent		1Be

Specimen 1Bf: embryonic day 16.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS24: cerebellum	Trace	Regionally restricted	1Bf	Expression is in a cluster in the region of the nuclear transitory zone. There is diffuse expression in the posterior region of the folium on presumptive Purkinje cell precursors.
TS24: cerebellar peduncle	Trace		1Bf
TS24: cerebellum external granule cell layer	Absent		1Bf

Specimen 2Aa: embryonic day 18.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum Purkinje cell layer	Present	Regionally restricted	2Aa	Expression is in the Purkinje cell layer of folia I-V. On folia VI-VIII and, to a lower extent, IX-X, strong expression was observed on putative Purkinje cells.
TS26: cerebellum	Present	Regionally restricted	2Aa	Expression is in a discrete region extending from the superior cerebellar peduncle toward the middle of the cerebellar plate, likely composed by fibers.

Specimen 2Ab: embryonic day 18.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum	Weak	Regionally restricted	2Ab	This mutant has a reduction in size and expression in the cerebellum primarily in the anterior folia I-III and IX-X.
TS26: cerebellum Purkinje cell layer	Weak	Regionally restricted	2Ab	This mutant has a reduction in size and expression in the cerebellum primarily in the anterior folia I-III and IX-X.

Specimen 2Ac: embryonic day 18.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum Purkinje cell layer	Present	Regionally restricted	2Ac	Expression is in the Purkinje cell layer of folia I-V. On folia VI-VIII and, to a lower extent, IX-X, strong expression was observed on putative Purkinje cells.
TS26: cerebellum	Present	Regionally restricted	2Ac	Expression is in a discrete region extending from the superior cerebellar peduncle toward the middle of the cerebellar plate, likely composed by fibers.

Specimen 2Ad: embryonic day 18.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum	Weak	Regionally restricted	2Ad	This mutant has a reduction in size and expression in the cerebellum primarily in the anterior folia I-III and IX-X.
TS26: cerebellum Purkinje cell layer	Weak	Regionally restricted	2Ad	This mutant has a reduction in size and expression in the cerebellum primarily in the anterior folia I-III and IX-X.

Specimen 2Ae: embryonic day 18.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum Purkinje cell layer	Present	Regionally restricted	2Ae	Expression is in the Purkinje cell layer of folia I-V. On folia VI-VIII and, to a lower extent, IX-X, strong expression was observed on putative Purkinje cells.
TS26: cerebellum	Present	Regionally restricted	2Ae	Expression is in a discrete region extending from the superior cerebellar peduncle toward the middle of the cerebellar plate, likely composed by fibers.

Specimen 2Af: embryonic day 18.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum	Weak	Regionally restricted	2Af	This mutant has a reduction in size and expression in the cerebellum primarily in the anterior folia I-III and IX-X.
TS26: cerebellum Purkinje cell layer	Weak	Regionally restricted	2Af	This mutant has a reduction in size and expression in the cerebellum primarily in the anterior folia I-III and IX-X.

Specimen 2Ag: embryonic day 18.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum Purkinje cell layer	Present	Regionally restricted	2Ag	Expression is in the Purkinje cell layer of folia I-V. On folia VI-VIII and, to a lower extent, IX-X, strong expression was observed on putative Purkinje cells.
TS26: cerebellum	Present	Regionally restricted	2Ag	Expression is in a discrete region extending from the superior cerebellar peduncle toward the middle of the cerebellar plate, likely composed by fibers.

Specimen 2Ah: embryonic day 18.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum	Weak	Regionally restricted	2Ah	This mutant has a reduction in size and expression in the cerebellum primarily in the anterior folia I-III and IX-X.
TS26: cerebellum Purkinje cell layer	Weak	Regionally restricted	2Ah	This mutant has a reduction in size and expression in the cerebellum primarily in the anterior folia I-III and IX-X.

Specimen 3Aa: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum Purkinje cell layer	Present	Graded	3Aa	Expression decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule I	Present	Regionally restricted	3Aa	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule II	Present	Regionally restricted	3Aa	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule III	Present	Regionally restricted	3Aa	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule IV	Present	Regionally restricted	3Aa	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule IX	Present	Regionally restricted	3Aa	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule V	Present	Regionally restricted	3Aa	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VI	Present	Regionally restricted	3Aa	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VII	Present	Regionally restricted	3Aa	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VIII	Present	Regionally restricted	3Aa	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule X	Present	Regionally restricted	3Aa	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.

Specimen 3Ab: postnatal day 0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Image
TS27: cerebellum posterior vermis	Present	3Ab
TS27: cerebellum vermis lobule VI	Present	3Ab
TS27: cerebellum vermis lobule VII	Present	3Ab
TS27: cerebellum vermis lobule VIII	Present	3Ab
TS27: cerebellum anterior vermis	Trace	3Ab
TS27: cerebellum vermis lobule I	Trace	3Ab
TS27: cerebellum vermis lobule II	Trace	3Ab
TS27: cerebellum vermis lobule III	Trace	3Ab
TS27: cerebellum vermis lobule IX	Trace	3Ab
TS27: cerebellum vermis lobule X	Trace	3Ab

Specimen 3Ac: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum Purkinje cell layer	Present	Graded	3Ac	Expression decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule I	Present	Regionally restricted	3Ac	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule II	Present	Regionally restricted	3Ac	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule III	Present	Regionally restricted	3Ac	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule IV	Present	Regionally restricted	3Ac	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule IX	Present	Regionally restricted	3Ac	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule V	Present	Regionally restricted	3Ac	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VI	Present	Regionally restricted	3Ac	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VII	Present	Regionally restricted	3Ac	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VIII	Present	Regionally restricted	3Ac	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule X	Present	Regionally restricted	3Ac	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.

Specimen 3Ad: postnatal day 0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Image
TS27: cerebellum posterior vermis	Present	3Ad
TS27: cerebellum vermis lobule VI	Present	3Ad
TS27: cerebellum vermis lobule VII	Present	3Ad
TS27: cerebellum vermis lobule VIII	Present	3Ad
TS27: cerebellum anterior vermis	Trace	3Ad
TS27: cerebellum vermis lobule I	Trace	3Ad
TS27: cerebellum vermis lobule II	Trace	3Ad
TS27: cerebellum vermis lobule III	Trace	3Ad
TS27: cerebellum vermis lobule IX	Trace	3Ad
TS27: cerebellum vermis lobule X	Trace	3Ad

Specimen 3Ae: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum Purkinje cell layer	Present	Graded	3Ae	Expression decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule I	Present	Regionally restricted	3Ae	Expression is in mostly Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule II	Present	Regionally restricted	3Ae	Expression is in mostly Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule III	Present	Regionally restricted	3Ae	Expression is in mostly Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule IV	Present	Regionally restricted	3Ae	Expression is in mostly Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule IX	Present	Regionally restricted	3Ae	Expression is in mostly Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule V	Present	Regionally restricted	3Ae	Expression is in mostly Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VI	Present	Regionally restricted	3Ae	Expression is in mostly Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VII	Present	Regionally restricted	3Ae	Expression is in mostly Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VIII	Present	Regionally restricted	3Ae	Expression is in mostly Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule X	Present	Regionally restricted	3Ae	Expression is in mostly Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.

Specimen 3Af: postnatal day 0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Image
TS27: cerebellum posterior vermis	Present	3Af
TS27: cerebellum vermis lobule VI	Present	3Af
TS27: cerebellum vermis lobule VII	Present	3Af
TS27: cerebellum vermis lobule VIII	Present	3Af
TS27: cerebellum anterior vermis	Trace	3Af
TS27: cerebellum vermis lobule I	Trace	3Af
TS27: cerebellum vermis lobule II	Trace	3Af
TS27: cerebellum vermis lobule III	Trace	3Af
TS27: cerebellum vermis lobule IX	Trace	3Af
TS27: cerebellum vermis lobule X	Trace	3Af

Specimen 3Ag: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum Purkinje cell layer	Present	Graded	3Ag	Expression decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule I	Present	Regionally restricted	3Ag	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule II	Present	Regionally restricted	3Ag	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule III	Present	Regionally restricted	3Ag	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule IV	Present	Regionally restricted	3Ag	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule IX	Present	Regionally restricted	3Ag	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule V	Present	Regionally restricted	3Ag	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VI	Present	Regionally restricted	3Ag	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VII	Present	Regionally restricted	3Ag	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule VIII	Present	Regionally restricted	3Ag	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.
TS27: cerebellum vermis lobule X	Present	Regionally restricted	3Ag	Expression is mostly in Purkinje cells and decreases from rostral (I-III) to caudal (IX-X) folia.

Specimen 3Ah: postnatal day 0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Image
TS27: cerebellum posterior vermis	Present	3Ah
TS27: cerebellum vermis lobule VI	Present	3Ah
TS27: cerebellum vermis lobule VII	Present	3Ah
TS27: cerebellum vermis lobule VIII	Present	3Ah
TS27: cerebellum vermis lobule I	Trace	3Ah
TS27: cerebellum vermis lobule II	Trace	3Ah
TS27: cerebellum vermis lobule III	Trace	3Ah
TS27: cerebellum vermis lobule IX	Trace	3Ah
TS27: cerebellum vermis lobule X	Trace	3Ah

Specimen 4Aa: postnatal day 3 (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum	Strong		4Aa

Specimen 4Ab: postnatal day 3; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum posterior vermis	Weak		4Ab
TS27: cerebellum anterior vermis	Trace		4Ab

Specimen 4Ac: postnatal day 3 (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum	Strong		4Ac

Specimen 4Ad: postnatal day 3; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum posterior vermis	Weak		4Ad
TS27: cerebellum anterior vermis	Trace		4Ad

Specimen 4Ae: postnatal day 3 (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum	Strong		4Ae

Specimen 4Af: postnatal day 3; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum posterior vermis	Weak		4Af
TS27: cerebellum anterior vermis	Trace		4Af

Specimen 4Ag: postnatal day 3 (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum	Strong		4Ag

Specimen 4Ah: postnatal day 3; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum posterior vermis	Weak		4Ah
TS27: cerebellum anterior vermis	Trace		4Ah

Specimen 5Aa: postnatal day 8 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Strong		5Aa
TS28: cerebellum internal granule cell layer	Strong		5Aa

Specimen 5Ab: postnatal day 8; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Present	Regionally restricted	5Ab	Expression was downregulated in folia I-III and was increased in folia VI-X.
TS28: cerebellum internal granule cell layer	Present	Regionally restricted	5Ab	Expression was downregulated in folia I-III and was increased in folia VI-X.
TS28: cerebellum vermis lobule IX	Strong	Regionally restricted	5Ab	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VI	Strong	Regionally restricted	5Ab	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VII	Strong	Regionally restricted	5Ab	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VIII	Strong	Regionally restricted	5Ab	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule X	Strong	Regionally restricted	5Ab	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule I	Weak	Regionally restricted	5Ab	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule II	Weak	Regionally restricted	5Ab	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule III	Weak	Regionally restricted	5Ab	Expression is in the Purkinje cell layer and internal granule cell layer.

Specimen 5Ac: postnatal day 8 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Strong		5Ac
TS28: cerebellum internal granule cell layer	Strong		5Ac

Specimen 5Ad: postnatal day 8; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Present	Regionally restricted	5Ad	Expression was downregulated in folia I-III and was increased in folia VI-X.
TS28: cerebellum internal granule cell layer	Present	Regionally restricted	5Ad	Expression was downregulated in folia I-III and was increased in folia VI-X.
TS28: cerebellum vermis lobule IX	Strong	Regionally restricted	5Ad	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VI	Strong	Regionally restricted	5Ad	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VII	Strong	Regionally restricted	5Ad	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VIII	Strong	Regionally restricted	5Ad	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule X	Strong	Regionally restricted	5Ad	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule I	Weak	Regionally restricted	5Ad	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule II	Weak	Regionally restricted	5Ad	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule III	Weak	Regionally restricted	5Ad	Expression is in the Purkinje cell layer and internal granule cell layer.

Specimen 5Ae: postnatal day 8 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Strong		5Ae
TS28: cerebellum internal granule cell layer	Strong		5Ae

Specimen 5Af: postnatal day 8; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Present	Regionally restricted	5Af	Expression was downregulated in folia I-III and was increased in folia VI-X.
TS28: cerebellum internal granule cell layer	Present	Regionally restricted	5Af	Expression was downregulated in folia I-III and was increased in folia VI-X.
TS28: cerebellum vermis lobule IX	Strong	Regionally restricted	5Af	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VI	Strong	Regionally restricted	5Af	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VII	Strong	Regionally restricted	5Af	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VIII	Strong	Regionally restricted	5Af	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule X	Strong	Regionally restricted	5Af	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule I	Weak	Regionally restricted	5Af	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule II	Weak	Regionally restricted	5Af	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule III	Weak	Regionally restricted	5Af	Expression is in the Purkinje cell layer and internal granule cell layer.

Specimen 5Ag: postnatal day 8 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Strong		5Ag
TS28: cerebellum internal granule cell layer	Strong		5Ag

Specimen 5Ah: postnatal day 8; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Present	Regionally restricted	5Ah	Expression was downregulated in folia I-III and was increased in folia VI-X.
TS28: cerebellum internal granule cell layer	Present	Regionally restricted	5Ah	Expression was downregulated in folia I-III and was increased in folia VI-X.
TS28: cerebellum vermis lobule IX	Strong	Regionally restricted	5Ah	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VI	Strong	Regionally restricted	5Ah	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VII	Strong	Regionally restricted	5Ah	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule VIII	Strong	Regionally restricted	5Ah	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule X	Strong	Regionally restricted	5Ah	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule I	Weak	Regionally restricted	5Ah	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule II	Weak	Regionally restricted	5Ah	Expression is in the Purkinje cell layer and internal granule cell layer.
TS28: cerebellum vermis lobule III	Weak	Regionally restricted	5Ah	Expression is in the Purkinje cell layer and internal granule cell layer.

Specimen 6Ca: embryonic day 16.0 (more

)

Structure	Level	Pattern	Image	Note
TS24: cerebellum	Present		6Ca

Specimen 6Cb: embryonic day 16.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS24: cerebellum	Weak		6Cb	Expression was 45% of that seen in wild-type.

Specimen 6Cc: embryonic day 18.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum	Present		6Cc

Specimen 6Cd: embryonic day 18.0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Pattern	Image	Note
TS26: cerebellum	Weak		6Cd	Expression was 45% of that seen in wild-type.

Specimen 6Ce: postnatal day 0 (more

)

Structure	Level	Image
TS27: cerebellum vermis lobule I	Present	6Ce
TS27: cerebellum vermis lobule II	Present	6Ce
TS27: cerebellum vermis lobule III	Present	6Ce

Specimen 6Cf: postnatal day 0; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Image	Note
TS27: cerebellum vermis lobule I	Weak	6Cf	Expression was 42% of that seen in wild-type.
TS27: cerebellum vermis lobule II	Weak	6Cf	Expression was 42% of that seen in wild-type.
TS27: cerebellum vermis lobule III	Weak	6Cf	Expression was 42% of that seen in wild-type.

Specimen 6Cg: postnatal day 3 (more

)

Structure	Level	Image
TS27: cerebellum vermis lobule I	Present	6Cg
TS27: cerebellum vermis lobule II	Present	6Cg
TS27: cerebellum vermis lobule III	Present	6Cg

Specimen 6Ch: postnatal day 3; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Image	Note
TS27: cerebellum vermis lobule I	Weak	6Ch	Expression was 51% of that seen in wild-type.
TS27: cerebellum vermis lobule II	Weak	6Ch	Expression was 51% of that seen in wild-type.
TS27: cerebellum vermis lobule III	Weak	6Ch	Expression was 51% of that seen in wild-type.

Specimen 6Ci: postnatal day 8 (more

)

Structure	Level	Image
TS28: cerebellum vermis lobule I	Present	6Ci
TS28: cerebellum vermis lobule II	Present	6Ci
TS28: cerebellum vermis lobule III	Present	6Ci

Specimen 6Cj: postnatal day 8; Ebf2^tm1.1Ggc/Ebf2^tm1.1Ggc (more

)

Structure	Level	Image	Note
TS28: cerebellum vermis lobule I	Weak	6Cj	Expression was 53% of that seen in wild-type.
TS28: cerebellum vermis lobule II	Weak	6Cj	Expression was 53% of that seen in wild-type.
TS28: cerebellum vermis lobule III	Weak	6Cj	Expression was 53% of that seen in wild-type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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