Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(tetO-ERBB2,-cre)#Mul
Name:	transgene insertion, William Muller
MGI ID:	MGI:6758107
Synonyms:	TetO-ERBB2FL-IRES-Cre
Transgene:	Tg(tetO-ERBB2,-cre)#Mul  Location: unknown
Alliance:	Tg(tetO-ERBB2,-cre)#Mul page

Strain of Origin:

Not Applicable

Transgene Type:    Transgenic (Inducible, Inserted expressed sequence, Recombinase) Inducer:    doxycycline/tetracycline Mutation:    Insertion   Tg(tetO-ERBB2,-cre)#Mul expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note bacteria tetO   Mutation details: A DNA fragment containing the Tet-responsive promoter driving a full-length human ERBB2 (ERBB2FL) and cre cDNA separated by IRES was used to generate the transgene. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:296966)

Activity:	Tissue activity of this recombinase allele
Driver:	tetO (bacteria) Summary of all recombinase alleles driven by tetO.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:296966 Smith HW, et al., An ErbB2 splice variant lacking exon 16 drives lung carcinoma. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20139-20148
All:	1 reference(s)