Wt1em1(cre/ERT2)Smoc
Endonuclease-mediated Allele Detail
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Symbol: |
Wt1em1(cre/ERT2)Smoc |
Name: |
WT1 transcription factor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
MGI ID: |
MGI:6758077 |
Synonyms: |
Wt1-CreERT2, Wt1em1(CreERT2-WPRE-pA)Smoc |
Gene: |
Wt1 Location: Chr2:104956874-105003959 bp, + strand Genetic Position: Chr2, 55.06 cM, cytoband E
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Alliance: |
Wt1em1(cre/ERT2)Smoc page
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Allele Type: |
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Endonuclease-mediated (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Wt1em1(cre/ERT2)Smoc expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Wt1 (MGI:98968) |
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Mutation details: A CreERT2-WPRE-pA expression cassette was knocked into the Wt1 gene start codon site. The cre activity was observed in the epicardium of the heart and in the mesothelia overlying most visceral organs after tamoxifen induction.
(J:238766)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Wt1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Wt1 Mutation: |
34 strains or lines available
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Original: |
J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017; |
All: |
1 reference(s) |
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