Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Prlhem1(cre)Mgmj
Name:	prolactin releasing hormone; endonuclease-mediated mutation 1, Martin G Myers, Jr
MGI ID:	MGI:6757218
Synonyms:	Prlhcre
Gene:	Prlh  Location: Chr1:90880830-90881749 bp, + strand  Genetic Position: Chr1, 45.81 cM
Alliance:	Prlhem1(cre)Mgmj page

Strain of Origin:

(C57BL/6J x SJL)F2

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Prlhem1(cre)Mgmj expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Prlh (MGI:3644668)     CRISPR/cas9 genome editing is used to insert an IRES and Cre recombinase at the stop codon. (J:309169)

Activity:	Tissue activity of this recombinase allele
Driver:	Prlh (mouse) Summary of all recombinase alleles driven by Prlh. Comparative matrix view of recombinase activities Alliance mouse Prlh gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prlh Mutation:	7 strains or lines available

Original:	J:309169 Cheng W, et al., NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity. Nat Commun. 2021 Aug 30;12(1):5175
All:	1 reference(s)