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Tg(Nfil3-EGFP,-icre)#Mfeu
Transgene Detail
Summary
Symbol: Tg(Nfil3-EGFP,-icre)#Mfeu
Name: transgene insertion, Markus Feuerer
MGI ID: MGI:6755588
Synonyms: Nfil3(GFP)
Transgene: Tg(Nfil3-EGFP,-icre)#Mfeu  Location: unknown  
Alliance: Tg(Nfil3-EGFP,-icre)#Mfeu page
Transgene
origin
Strain of Origin:  C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Recombinase, Reporter)
Mutation:    Insertion
 
Tg(Nfil3-EGFP,-icre)#Mfeu expression driven by 1 gene
 
Mutation detailsUsing a bacterial artificial chromosome (BAC: RP23-227M5) homologous recombination, a transgene with an eGFP-2A-iCre cassette was inserted at the start codon of the mouse Nfil3 gene in exon 2 was generated. The recombinant BAC transgene was then injected into fertilized C57BL/6N mouse eggs. Three lines were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:288341)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nfil3 (mouse)
Summary of all recombinase alleles driven by Nfil3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:288341 Delacher M, et al., Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF. Immunity. 2020 Feb 18;52(2):295-312.e11
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory