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Gene Expression Data
Assay Details
Assay
Reference: J:308800 Ah-Cann C, et al., A functional genetic screen identifies aurora kinase b as an essential regulator of Sox9-positive mouse embryonic lung progenitor cells. Development. 2021 Jul 1;148(13):dev199543
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6755206
Gene symbol: Aurkb
Gene name: aurora kinase B
Results
Specimen S3B E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung epithelium Strong S3B E13.5 High levels of expression in both endoderm and mesoderm.
TS21: lung mesenchyme Strong S3B E13.5 High levels of expression in both endoderm and mesoderm.
Specimen S3B E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung epithelium Strong S3B E14.5 High levels of expression in both endoderm and mesoderm.
TS22: lung mesenchyme Strong S3B E14.5 High levels of expression in both endoderm and mesoderm.
Specimen S3B E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lung Present S3B E15.5 Lower levels of expression at E15.5.
Specimen 3B E13.5 Aurkb: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung epithelium Strong Regionally restricted 3B E13.5 Aurkb Expression in both endoderm and mesoderm. High expression in Sox9+ cells, but not exclusively.
TS21: lung mesenchyme Strong Regionally restricted 3B E13.5 Aurkb Expression in both endoderm and mesoderm. High expression in Sox9+ cells, but not exclusively.
Specimen 3B E15.5 Aurkb: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lung epithelium Present Regionally restricted 3B E15.5 Aurkb Expression in both endoderm and mesoderm. High expression in Sox9+ cells, but not exclusively.
TS23: lung mesenchyme Present Regionally restricted 3B E15.5 Aurkb Expression in both endoderm and mesoderm. High expression in Sox9+ cells, but not exclusively.
Specimen 3B E17.5 Aurkb: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lung Weak Regionally restricted 3B E17.5 Aurkb Expression dramatically reduced. No expression in Sox9+ cells at E17.5.
TS25: lung epithelium Trace Regionally restricted 3B E17.5 Aurkb Expression in only a small number of Cdh1+ cells epithelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory