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Gene Expression Data
Assay Details
Assay
Reference: J:216142 Amann R, et al., The FgfrL1 receptor is required for development of slow muscle fibers. Dev Biol. 2014 Oct 15;394(2):228-41
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6753278
Gene symbol: Myh7
Gene name: myosin, heavy polypeptide 7, cardiac muscle, beta
Antibody: Anti-beta-MHC NOQ7.5.4D (M8421, MAB1628)
Detection system: Secondary antibody coupled to rhodamine
Results
Specimen 9 E18.5 wt: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: diaphragm dome Present Regionally restricted 9_upper left Expressed in approximately 20% of all muscle fibers. Expressed in slow muscle fibers.

Specimen 9 E18.5 ko: embryonic day 18.5; Fgfrl1tm1True/Fgfrl1tm1True (more )
Structure Level Pattern Image Note
TS26: diaphragm dome Present Regionally restricted 9_upper right Overall staining was much weaker compared with the wild-type. Only expressed in very few fibers.

Specimen 9 E15.5 wt: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: diaphragm dome Strong Regionally restricted 9_lower left Expressed in slow muscle fibers.

Specimen 9 E15.5 ko: embryonic day 15.5; Fgfrl1tm1True/Fgfrl1tm1True (more )
Structure Level Pattern Image Note
TS23: diaphragm dome Strong Regionally restricted 9_lower right Expressed in slow muscle fibers, similar as in the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory