Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Oprm1em1(icre/ERT2)Ygs
Name:	opioid receptor, mu 1; endonuclease-mediated mutation 1, Yan-Gang Sun
MGI ID:	MGI:6739854
Synonyms:	MOR-iCreERT2
Gene:	Oprm1  Location: Chr10:6708593-6988209 bp, + strand  Genetic Position: Chr10, 1.85 cM, cytoband A2
Alliance:	Oprm1em1(icre/ERT2)Ygs page

Strain of Origin:

C57BL/6

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Oprm1em1(icre/ERT2)Ygs expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Oprm1 (MGI:97441)   Mutation details: Using CRISPR/Cas9 technology a cassette comprising of the P2A-iCreERT2-WPRE was inserted into exon 2 of the mouse opioid receptor (Oprm1) gene. (J:291061)

Activity:	Tissue activity of this recombinase allele
Driver:	Oprm1 (mouse) Summary of all recombinase alleles driven by Oprm1. Comparative matrix view of recombinase activities Alliance mouse Oprm1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oprm1 Mutation:	53 strains or lines available

Original:	J:291061 Zhang XY, et al., Different neuronal populations mediate inflammatory pain analgesia by exogenous and endogenous opioids. Elife. 2020 Jun 10;9:e55289
All:	1 reference(s)