Gene Expression Data
Assay Details
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Assay
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Reference:
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J:305814
Walton SL, et al., Insulin-regulated aminopeptidase deficiency impairs cardiovascular adaptations and placental development during pregnancy. Clin Sci (Lond). 2020 Dec 11;134(23):3213-3228
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6739826
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Gene symbol:
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Lnpep
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Gene name:
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leucyl/cystinyl aminopeptidase
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Antibody:
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IRAP antibody (6918)
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
6A:
embryonic day 18.5
(more  )
Specimen
6A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: labyrinthine zone |
Present |
Regionally restricted |
6B
,
6A
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Expression is in the labyrinthine syncytiotrophoblasts.
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| TS28: placenta |
Present |
Regionally restricted |
6B
,
6A
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Expression is in the labyrinthine syncytiotrophoblasts.
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| TS26: extraembryonic component |
Present |
Regionally restricted |
6B
,
6A
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Expression is in the junctional zone in parietal trophoblast cells and is absent in spongiotrophoblasts and in the endothelial cells lining the fetal blood sinuses. Endothelial cells lining the maternal blood sinuses in the junctional zone had very strong expression.
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Specimen
6A mother:
postnatal adult
(more )
Specimen
6A mother:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Female
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: placenta |
Present |
Regionally restricted |
6A
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Expression is in the labyrinthine syncytiotrophoblasts.
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Specimen
6A inset:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Lnpeptm1.1Sych/Lnpeptm1.1Sych
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Analysis Tools