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Gene Expression Data
Assay Details
Assay
Reference: J:178264 Kraft M, et al., Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice. J Clin Invest. 2011 Sep 1;121(9):3479-91
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6731042
Gene symbol: Kat6b
Gene name: K(lysine) acetyltransferase 6B
Reporter: lacZ
Direct Detection
Results
Specimen 4H: embryonic day 15.5; Kat6bGt(pKC199)1Pgr/Kat6b+ (more )
Structure Level Pattern Image Note
TS23: limb mesenchyme Present Regionally restricted 4H Strong expression is seen in mesenchyme surrounding cartilage primordia of the developing skeletal system.
Specimen 4I: embryonic day 15.5; Kat6bGt(pKC199)1Pgr/Kat6b+ (more )
Structure Level Pattern Image Note
TS23: limb mesenchyme Present Regionally restricted 4I Strong expression is seen in mesenchyme surrounding cartilage primordia of the developing skeletal system.
Specimen 4J: embryonic day 12.5; Kat6bGt(pKC199)1Pgr/Kat6b+ (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 4J
TS20: skeletal system Present 4J Expression is seen in skeletal elements.
TS20: mandible primordium Present 4J
Specimen 4K: postnatal adult; Kat6bGt(pKC199)1Pgr/Kat6b+ (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 4K
TS28: parietal cortex Present 4K
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory