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Gene Expression Data
Assay Details
Assay
Reference: J:296399 Bartoletti G, et al., Pdgfra regulates multipotent cell differentiation towards chondrocytes via inhibiting Wnt9a/beta-catenin pathway during chondrocranial cartilage development. Dev Biol. 2020 Oct 1;466(1-2):36-46
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6730091
Gene symbol: Pdgfra
Gene name: platelet derived growth factor receptor, alpha polypeptide
Results
Specimen S1 A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nasal septum cartilage Present Single cells S1A Expression is in chondrocytes.
Specimen S1 B: embryonic day 14.5; Pdgfratm11(EGFP)Sor/Pdgfratm11(EGFP)Sor (more )
Structure Level Pattern Image Note
TS22: nasal septum cartilage Absent S1B
Specimen S4 no cre: embryonic day 14.5; Pdgfratm12Sor/Pdgfra+ (more )
Structure Level Pattern Image Note
TS22: cartilage Present Regionally restricted S4_no cre Expression is in the tectum transversum.
TS22: chondrocranium Present Regionally restricted S4_no cre Expression is in the tectum transversum.
Specimen S4 Col2a1Cre: embryonic day 14.5; Pdgfratm12Sor/Pdgfra+, Tg(Col2a1-cre)1Asz/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cartilage Strong S4_Col2a1Cre Expression is in the tectum transversum.
TS22: chondrocranium Strong S4_Col2a1Cre Expression is in the tectum transversum.
Specimen S4 Mesp1Cre: embryonic day 14.5; Pdgfratm12Sor/Pdgfra+, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cartilage Strong S4_Mesp1Cre Expression is in the tectum transversum.
TS22: chondrocranium Strong S4_Mesp1Cre Expression is in the tectum transversum.
Specimen S4 Wnt1Cre2: embryonic day 14.5; E2f1Tg(Wnt1-cre)2Sor/E2f1+, Pdgfratm12Sor/Pdgfra+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: chondrocranium Strong S4_Wnt1Cre2 Expression is in the tectum transversum.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory