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Gene Expression Data
Assay Details
Assay
Reference: J:287184 Huang K, et al., Annexin A3 is necessary for parallel artery-vein alignment in the mouse retina. Dev Dyn. 2020 May;249(5):666-678
Assay type: RNA in situ
MGI Accession ID: MGI:6729946
Gene symbol: Anxa3
Gene name: annexin A3
Probe: Anxa3 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2E: embryonic day 9.5; Anxa3tm1c(EUCOMM)Hmgu/Anxa3tm1c(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS15: dorsal aorta Present 2E
TS15: head Present 2E
TS15: heart Present 2E
TS15: intersomitic blood vessel Present 2E
TS15: somite Present 2E
Specimen 2F: embryonic day 9.5; Anxa3tm1c(EUCOMM)Hmgu/Anxa3tm1c(EUCOMM)Hmgu, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: cardiovascular system endothelium Absent 2F Authors report loss of expression in endothelium.
TS15: dorsal aorta Weak 2F Significantly reduced expression in dorsal aorta and intersomitic vessels.
TS15: intersomitic blood vessel Weak 2F Significantly reduced expression in dorsal aorta and intersomitic vessels.
TS15: head Present 2F Nonvascular expression in head region, heart and somtes is retained.
TS15: heart Present 2F Nonvascular expression in head region, heart and somtes is retained.
TS15: somite Present 2F Nonvascular expression in head region, heart and somtes is retained.
Specimen 3A/3B: postnatal day 7; Anxa3tm1c(EUCOMM)Hmgu/Anxa3tm1c(EUCOMM)Hmgu (more )
Note: Double labeled: black - Anxa3; white - Isolectin-IB4
Structure Level Pattern Image Note
TS28: retina blood vessel Present Regionally restricted 3B , 3A Expression in vasculature of retina. Expression predominantly localized to arteries and veins, and to a lesser extent in intervening capillaries.
Specimen 3C/3D: postnatal day 7; Anxa3tm1c(EUCOMM)Hmgu/Anxa3tm1c(EUCOMM)Hmgu, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: black - Anxa3; white - Isolectin-IB4
Structure Level Pattern Image Note
TS28: retina blood vessel Trace Regionally restricted 3D , 3C Expression largely absent. Residual expression in vasculature.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory