Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Grprtm2(icre)Zfc
Name:	gastrin releasing peptide receptor; targeted mutation 2, Zhou-Feng Chen
MGI ID:	MGI:6729692
Synonyms:	Grpricre, Grprtm2.1(icre)Zfc
Gene:	Grpr  Location: ChrX:162296900-162332673 bp, - strand  Genetic Position: ChrX, 75.63 cM
Alliance:	Grprtm2(icre)Zfc page

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Grprtm2(icre)Zfc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Grpr (MGI:95836)   Mutation details: The targeting vector was designed to insert an internal ribosome entry site (IRES) fused to a codon improved cre recombinase (icre), followed by a frt-flanked neomycin resistance (neo) cassette in opposite orientation, immediately downstream of the stop codon in the 3' UTR. (J:101977)

Activity:	Tissue activity of this recombinase allele
Driver:	Grpr (mouse) Summary of all recombinase alleles driven by Grpr. Alliance mouse Grpr gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grpr Mutation:	14 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	3 reference(s)