Aurka Western blot Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:198479 Sasai K, et al., Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality. Oncogene. 2008 Jul 3;27(29):4122-7
Assay type:	Western blot
MGI Accession ID:	MGI:6729260
Gene symbol:	Aurka
Gene name:	aurora kinase A

Antibody:

anti-Aurora A

Results

Image: 1d Aur-A

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Genetic Background	Mutant Allele(s)	Sex
+/+	P adult	TS28: testis	Present	involves: C57BL/6		Male
+/+	P adult	TS28: testis	Present	involves: C57BL/6		Male
+/-	P adult	TS28: testis	Weak (a)	involves: 129S7/SvEvBrd * C57BL/6	Aurka^tm1.2Sbsn/Aurka⁺	Male
+/-	P adult	TS28: testis	Weak (a)	involves: 129S7/SvEvBrd * C57BL/6	Aurka^tm1.2Sbsn/Aurka⁺	Male
CN/CN	P adult	TS28: testis	Present (b)	involves: 129S7/SvEvBrd * C57BL/6	Aurka^tm1Sbsn/Aurka^tm1Sbsn	Male
CN/CN	P adult	TS28: testis	Present (b)	involves: 129S7/SvEvBrd * C57BL/6	Aurka^tm1Sbsn/Aurka^tm1Sbsn	Male
C/C	P adult	TS28: testis	Present (b)	involves: 129S7/SvEvBrd * C57BL/6	Aurka^tm1.1Sbsn/Aurka^tm1.1Sbsn	Male
C/C	P adult	TS28: testis	Present (b)	involves: 129S7/SvEvBrd * C57BL/6	Aurka^tm1.1Sbsn/Aurka^tm1.1Sbsn	Male
C/-	P adult	TS28: testis	Weak (a)	involves: 129S7/SvEvBrd * C57BL/6	Aurka^tm1.1Sbsn/Aurka^tm1.2Sbsn	Male
C/-	P adult	TS28: testis	Weak (a)	involves: 129S7/SvEvBrd * C57BL/6	Aurka^tm1.1Sbsn/Aurka^tm1.2Sbsn	Male
Liver	P adult	TS28: liver	Absent	involves: C57BL/6		Not Specified
NIH3T3	Control

Notes:
(a) Band intensities suggest that the null allele was silenced.
(b) Band intensities suggest that the CN and C alleles express comparable amounts of protein as wild-type allele.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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