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Gene Expression Data
Assay Details
Assay
Reference: J:222281 Balboula AZ, et al., RBBP4 regulates histone deacetylation and bipolar spindle assembly during oocyte maturation in the mouse. Biol Reprod. 2015 Apr;92(4):105
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6729246
Gene symbol: Rbbp4
Gene name: retinoblastoma binding protein 4, chromatin remodeling factor
Results
Specimen 1B GV: postnatal week 6 (more )
Note: Germinal vesicle oocyte.
Structure Level Pattern Image Note
TS28: primary oocyte Present Regionally restricted 1B GV RBBP4 , 1B GV Merge Expession localized in nucleus.
Specimen S1 GV: postnatal week 6 (more )
Note: Germinal vesicle oocyte.
Structure Level Pattern Image Note
TS28: primary oocyte Present Regionally restricted S1_GV Merge , S1_GV RBBP4 Expession localized in nucleus.
Specimen 1B Met I: postnatal week 6 (more )
Note: Metaphase I egg.
Structure Level Pattern Image Note
TS28: oocyte Ambiguous Regionally restricted 1B Met I Merge , 1B Met I RBBP4 Failure to detect expression in Met I and Met II oocytes reflects ~30-fold dilution upon diffusion into cytoplasm following germinal vesicle breakdown.
Specimen 1B Met II: postnatal week 6 (more )
Note: Metaphase II egg.
Structure Level Pattern Image Note
TS28: secondary oocyte Ambiguous Regionally restricted 1B Met II RBBP4 , 1B Met II Merge Failure to detect expression in Met I and Met II oocytes reflects ~30-fold dilution upon diffusion into cytoplasm following germinal vesicle breakdown.
Specimen S1 Met II: postnatal week 6 (more )
Note: Metaphase II egg.
Structure Level Pattern Image Note
TS28: secondary oocyte Trace Regionally restricted S1_Magn. RBBP4 , S1_Magn. Merge , S1_Met I Merge , S1_Met I RBBP4 At higher magnification, faint expression localized in chromatin.
Specimen 1B 1C: embryonic day 0.5 (more )
Note: 1-cell embryo.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Regionally restricted 1B 1C RBBP4 , 1B 1C Merge Expression in pronuclei.
Specimen 1B 2C: embryonic day 1.0 (more )
Note: 2-cell embryo.
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Ambiguous 1B 2C Merge , 1B 2C RBBP4 Expression not described.
Specimen 1B 8C: embryonic day 2.5 (more )
Note: 8-cell embryo.
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Ambiguous 1B 8C Merge , 1B 8C RBBP4 Expression not described.
Specimen 1B BL: embryonic day 3.5 (more )
Note: Blastocyst.
Structure Level Pattern Image Note
TS4: blastocyst Ambiguous 1B BL Merge , 1B BL RBBP4 Expression not described.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory