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Gene Expression Data
Assay Details
Assay
Reference: J:130321 Sato H, et al., Visualizing expression patterns of Shh and Foxf1 genes in the foregut and lung buds by optical projection tomography. Pediatr Surg Int. 2008 Jan;24(1):3-11
Assay type: RNA in situ
MGI Accession ID: MGI:6728870
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe198
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: embryo Present 1A Authors state the precise domain of ventral localization could not be ascertained from whole mounts.
Specimen 1B: embryonic day 9.0 (more )
Note: Imaged by optical projection tomography (OPT).
Structure Level Pattern Image Note
TS14: foregut Present 1B
TS14: neural tube Present 1B
TS14: notochord Present 1B
Specimen 1C: embryonic day 9.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS14: foregut Present Regionally restricted 1C Expression localized to ventral aspect of foregut invagination at level of branchial arches.
Specimen 1D: embryonic day 9.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS14: foregut Present Regionally restricted 1D Expression ventrally restricted in foregut.
Specimen 1E: embryonic day 9.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS14: foregut Present Regionally restricted 1E Expression ventrally restricted in foregut.
Specimen 1F: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: foregut Present 1F
TS16: hindgut Present 1F
TS16: neural tube Present 1F
TS16: notochord Present 1F
Specimen 1G: embryonic day 10.0 (more )
Note: Imaged by optical projection tomography (OPT).
Structure Level Pattern Image Note
TS16: laryngo-tracheal groove Present Regionally restricted 1G Expression restricted to ventral endoderm of laryngotracheal groove, including site of division of repiratory groove from foregut.
Specimen 1H: embryonic day 10.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS16: lung Present 1H
Specimen 1I: embryonic day 10.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS16: foregut Present Regionally restricted 1I Ventral expression in anterior foregut.
Specimen 1J: embryonic day 10.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS16: lung Present 1J
Specimen 1K: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: neural tube floor plate Present 1K
TS18: forelimb bud Present 1K Expression in polarizing regions of forelimb and hindlimb buds.
TS18: hindlimb bud Present 1K Expression in polarizing regions of forelimb and hindlimb buds.
TS18: gut Ambiguous 1K Expression in gut was no longer clearly visible externally.
Specimen 1L: embryonic day 11.0 (more )
Note: Imaged by optical projection tomography (OPT).
Structure Level Pattern Image Note
TS18: forelimb bud Present Regionally restricted 1L Expression in polarizing regions of forelimb and hindlimb buds.
TS18: hindlimb bud Present Regionally restricted 1L Expression in polarizing regions of forelimb and hindlimb buds.
TS18: gut Present 1L Expression in gut clearly visible with OPT scanning.
Specimen 1M: embryonic day 11.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS18: laryngo-tracheal groove Present Regionally restricted 1M Expression at division of trachea from foregut.
Specimen 1N: embryonic day 11.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS18: foregut Present 1N
TS18: lung Present 1N
TS18: trachea Present 1N
Specimen 1O: embryonic day 11.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS18: respiratory tract Present Regionally restricted 1O Expression extending into dorsal terrisory in more caudal sections.
Specimen 1P: embryonic day 11.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS18: respiratory tract Present Regionally restricted 1P Expression extending into dorsal terrisory in more caudal sections.
Specimen 1Q: embryonic day 11.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS18: lung Present 1Q
Specimen 2A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present 2A
TS20: stomach Present 2A
Specimen 2B: embryonic day 12.0 (more )
Note: Imaged by optical projection tomography (OPT).
Structure Level Pattern Image Note
TS20: spinal cord floor plate Present 2B
TS20: esophagus epithelium Present 2B Expression in endoderm of esophagus.
TS20: lung Present 2B
Specimen 2C: embryonic day 12.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS20: esophagus epithelium Present 2C Expression in endoderm of esophagus.
Specimen 2D: embryonic day 12.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS20: lung epithelium Present 2D Expression in endoderm of lung buds.
Specimen 2E: embryonic day 12.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS20: esophagus epithelium Present 2E Expression in endoderm of esophagus.
Specimen 2F: embryonic day 12.0 (more )
Note: Image is a virtual section generated from OPT.
Structure Level Pattern Image Note
TS20: lung epithelium Present 2F Expression in endoderm of lung buds.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory