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Gene Expression Data
Assay Details
Assay
Reference: J:303715 Woodruff ED, et al., Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development. Dev Biol. 2021 Apr;472:67-74
Assay type: RNA in situ
MGI Accession ID: MGI:6728865
Gene symbol: Tfap2a
Gene name: transcription factor AP-2, alpha
Probe: Tfap2a cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 12.5 (more )
Note: Early bud stage of tooth development.
Structure Level Pattern Image Note
TS20: jaw primordium epithelium Present 1A
TS20: oral epithelium Present 1A
TS20: early bud stage tooth Present Regionally restricted 1A Expression is in the incisor epithelium and mesenchyme.
Specimen 1B: embryonic day 12.5 (more )
Note: Early bud stage of tooth development.
Structure Level Pattern Image Note
TS20: jaw primordium epithelium Present 1B
TS20: oral epithelium Present 1B
TS20: early bud stage tooth Present Regionally restricted 1B Expression is in the incisor epithelium and mesenchyme.
Specimen 1C: embryonic day 12.5 (more )
Note: Early bud stage of tooth development.
Structure Level Pattern Image Note
TS20: jaw primordium epithelium Present 1C
TS20: oral epithelium Present 1C
TS20: early bud stage tooth Present Regionally restricted 1C Expression is in the molar bud mesenchye.
Specimen 1G: embryonic day 13.5 (more )
Note: Late bud stage of tooth development.
Structure Level Pattern Image Note
TS21: oral epithelium Present 1G
TS21: upper jaw epithelium Present 1G
TS21: upper jaw incisor epithelium Present 1G
TS21: upper jaw incisor mesenchyme Present 1G
Specimen 1H: embryonic day 13.5 (more )
Note: Late bud stage of tooth development.
Structure Level Pattern Image Note
TS21: lower jaw epithelium Present 1H
TS21: lower jaw incisor epithelium Present 1H
TS21: lower jaw incisor mesenchyme Present 1H
TS21: oral epithelium Present 1H
Specimen 1I: embryonic day 13.5 (more )
Note: Late bud stage of tooth development.
Structure Level Pattern Image Note
TS21: molar mesenchyme Present 1I
TS21: oral epithelium Present 1I
Specimen 1M: embryonic day 14.5 (more )
Note: Cap stage of tooth development.
Structure Level Pattern Image Note
TS22: oral epithelium Present 1M
TS22: upper jaw epithelium Present 1M
TS22: upper jaw incisor epithelium Present 1M
TS22: upper jaw incisor mesenchyme Present 1M
Specimen 1N: embryonic day 14.5 (more )
Note: Cap stage of tooth development.
Structure Level Pattern Image Note
TS22: lower jaw epithelium Present 1N
TS22: lower jaw incisor epithelium Present 1N
TS22: lower jaw incisor mesenchyme Present 1N
TS22: oral epithelium Present 1N
Specimen 1O: embryonic day 14.5 (more )
Note: Cap stage of tooth development.
Structure Level Pattern Image Note
TS22: molar mesenchyme Present 1O
TS22: oral epithelium Present 1O
Specimen 2A: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: bell stage tooth Present 2A
TS25: upper jaw incisor epithelium Present 2A
TS25: upper jaw incisor mesenchyme Present 2A
Specimen 2E: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: bell stage tooth Weak 2E
TS25: lower jaw incisor epithelium Weak 2E
Specimen 2I: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: bell stage tooth Present 2I
TS25: upper jaw molar epithelium Present 2I
TS25: inner enamel epithelium Present Regionally restricted 2I Expression is in the inner enamel epithelium directly adjacent to the dental mesenchyme.
Specimen 2M: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: bell stage tooth Present 2M
TS25: lower jaw molar epithelium Present 2M
TS25: inner enamel epithelium Present Regionally restricted 2M Expression is in the inner enamel epithelium directly adjacent to the dental mesenchyme.
Specimen S2A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: eye Present S2A
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory