Tg(NPHS2-cre/ERT2)#Hika
Transgene Detail
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Symbol: |
Tg(NPHS2-cre/ERT2)#Hika |
Name: |
transgene insertion, Hiroshi Kawachi |
MGI ID: |
MGI:6728122 |
Synonyms: |
Nphs2-CreERT2 |
Transgene: |
Tg(NPHS2-cre/ERT2)#Hika Location: unknown
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Alliance: |
Tg(NPHS2-cre/ERT2)#Hika page
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Strain of Origin: |
C57BL/6J x C3H/HeJ
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(NPHS2-cre/ERT2)#Hika expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Homolog in Mouse |
Note |
human |
NPHS2 (7827) |
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Mutation details: The transgene contains CreERT2 under the control of the 2.6-kb promoter of the human NPHS2 to drive cre/ERT2 expression in podocytes. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:293123)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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NPHS2
(human)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:293123 Fukusumi Y, et al., Nephrin-Binding Ephrin-B1 at the Slit Diaphragm Controls Podocyte Function through the JNK Pathway. J Am Soc Nephrol. 2018 May;29(5):1462-1474 |
All: |
2 reference(s) |
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