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Tg(NPHS2-cre/ERT2)#Hika
Transgene Detail
Summary
Symbol: Tg(NPHS2-cre/ERT2)#Hika
Name: transgene insertion, Hiroshi Kawachi
MGI ID: MGI:6728122
Synonyms: Nphs2-CreERT2
Transgene: Tg(NPHS2-cre/ERT2)#Hika  Location: unknown  
Alliance: Tg(NPHS2-cre/ERT2)#Hika page
Transgene
origin
Strain of Origin:  C57BL/6J x C3H/HeJ
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(NPHS2-cre/ERT2)#Hika expression driven by 1 gene
 
Mutation detailsThe transgene contains CreERT2 under the control of the 2.6-kb promoter of the human NPHS2 to drive cre/ERT2 expression in podocytes. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:293123)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: NPHS2 (human)
Summary of all recombinase alleles driven by NPHS2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:293123 Fukusumi Y, et al., Nephrin-Binding Ephrin-B1 at the Slit Diaphragm Controls Podocyte Function through the JNK Pathway. J Am Soc Nephrol. 2018 May;29(5):1462-1474
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory