Foxp2tm1.1(flpo)Tmj
Targeted Allele Detail
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Symbol: |
Foxp2tm1.1(flpo)Tmj |
Name: |
forkhead box P2; targeted mutation 1.1, Thomas M Jessell |
MGI ID: |
MGI:6728072 |
Synonyms: |
FoxP2::Flpo |
Gene: |
Foxp2 Location: Chr6:14901348-15441976 bp, + strand Genetic Position: Chr6, 6.49 cM, cytoband A2
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Alliance: |
Foxp2tm1.1(flpo)Tmj page
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Germline Transmission: |
Earliest citation of germline transmission:
J:234419
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout, Recombinase) |
Mutation: |
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Insertion
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Foxp2tm1.1(flpo)Tmj expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A codon-optimized version of FLP recombinase (Flpo) was inserted into the ATG in the 4th exon of the Fox2 genomic locus by ES cell recombination. The neomycin selectable cassette was removed by crossing with cre-deleter. This is a null allele as well as recombinase knock-in.
(J:234419)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Foxp2
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Foxp2 Mutation: |
52 strains or lines available
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Original: |
J:234419 Bikoff JB, et al., Spinal Inhibitory Interneuron Diversity Delineates Variant Motor Microcircuits. Cell. 2016 Mar 24;165(1):207-19 |
All: |
2 reference(s) |
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