Tg(Gcg-icre/ERT2)17Reim
Transgene Detail
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| Symbol: |
Tg(Gcg-icre/ERT2)17Reim |
| Name: |
transgene insertion 17, Frank Reimann |
| MGI ID: |
MGI:6727381 |
| Synonyms: |
GLU-CreERT2-17 |
| Transgene: |
Tg(Gcg-icre/ERT2)17Reim Location: unknown
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| Alliance: |
Tg(Gcg-icre/ERT2)17Reim page
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| Strain of Origin: |
C57BL/6 x CBA
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Gcg-icre/ERT2)17Reim expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Gcg (MGI:95674) |
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Mutation details: The transgene based on murine BAC clone (RP23-343C17) containing the sequence between the proglucagon start codon in exon 2 and stop codon in exon 6 was used to express iCreERT2 under the control of the proglucagon promoter. Initially, two transgenic lines 9 and 17 were established both with an estimated transgene copy number of one. The initial characterization did not reveal any differences.
(J:295333)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Gcg
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:295333 Campbell JR, et al., Essential Role of Syntaxin-Binding Protein-1 in the Regulation of Glucagon-Like Peptide-1 Secretion. Endocrinology. 2020 May 1;161(5) |
| All: |
1 reference(s) |
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Analysis Tools
