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Gene Expression Data
Assay Details
Assay
Reference: J:185870 Hazen VM, et al., BMP receptor-activated Smads confer diverse functions during the development of the dorsal spinal cord. Dev Biol. 2012 Jul 15;367(2):216-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6727050
Gene symbol: Atoh1
Gene name: atonal bHLH transcription factor 1
Antibody: anti-MATH1
Detection system: Secondary antibody
Results
Specimen 4B: embryonic day 10.5; Smad1tm1Abr/Smad1tm1Abr (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4B Expressed in dorsal progenitor 1 cells.
Specimen 4F: embryonic day 10.5; Smad1tm1Abr/Smad1tm1Abr, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4F Expressed in dorsal progenitor 1 cells, similar as in the control.
Specimen 4J: embryonic day 10.5; Smad5tm1Huy/Smad5tm1Huy (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4J Expressed in dorsal progenitor 1 cells.
Specimen 4N: embryonic day 10.5; Smad5tm1Huy/Smad5tm1Huy, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4N Reduced expression (>20%) in dorsal progenitor 1 cells, compared with the control.
Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted Expressed in dorsal progenitor 1 cells.
Specimen not shown: embryonic day 10.5; Smad1tm1Abr/Smad1tm1Abr, Smad5tm1Huy/Smad5tm1Huy, Tg(Atoh1-cre)1Bfri/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted Reduced expression (25%) in dorsal progenitor 1 cells, compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory