Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Atoh7tm3(cre/ERT2)Xmu
Name:	atonal bHLH transcription factor 7; targeted mutation 3, Xiuqian Mu
MGI ID:	MGI:6727035
Synonyms:	Atoh7zsGreenCreERT2
Gene:	Atoh7  Location: Chr10:62935564-62937059 bp, + strand  Genetic Position: Chr10, 32.54 cM
Alliance:	Atoh7tm3(cre/ERT2)Xmu page

Germline Transmission:	Earliest citation of germline transmission: J:297659
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Inducible, Null/knockout, Recombinase, Reporter) Inducer:    tamoxifen Mutations:    Insertion, Intragenic deletion   Atoh7tm3(cre/ERT2)Xmu expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Atoh7 (MGI:1355553)   Mutation details: The zsGreen-T2A-CreERT2-SV40 poly(A)-LoxP-Neo-LoxP cassette replaced Atoh7 ORF by homologous recombination in the ES cells. It is a null allele designed to express both zsGreen and CreERT2 from the Atoh7 promoter. (J:297659)

Activity:	Tissue activity of this recombinase allele
Driver:	Atoh7 (mouse) Summary of all recombinase alleles driven by Atoh7. Comparative matrix view of recombinase activities Alliance mouse Atoh7 gene page

In Mice Carrying this Mutation:

16 assay results 2 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atoh7 Mutation:	9 strains or lines available

Original:	J:297659 Ge Y, et al., Two new genetically modified mouse alleles labeling distinct phases of retinal ganglion cell development by fluorescent proteins. Dev Dyn. 2020 Aug 2;
All:	2 reference(s)