Tg(Runx1/Hspa1a-EGFP)542Mosa
Transgene Detail
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| Symbol: |
Tg(Runx1/Hspa1a-EGFP)542Mosa |
| Name: |
transgene insertion 542, Motomi Osato |
| MGI ID: |
MGI:6726475 |
| Synonyms: |
Runx1 +24 mCNE #542 |
| Transgene: |
Tg(Runx1/Hspa1a-EGFP)542Mosa Location: unknown
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| Alliance: |
Tg(Runx1/Hspa1a-EGFP)542Mosa page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The transgenic construct contains mouse Runx1 enhancer element sequence (eR1) also called Runx1 +24 mouse conserved noncoding element (mCNE) and the mouse Hspa1a (heat-shock protein 68) basal promoter sequence driving the expression of EGFP. Three distinct founder lines numbered 523, 540, and 542 were established. Although variation in the intensity of GFP fluorescence was observed, all three lines showed similar reporter gene expression patterns at sites of hematopoietic stem cell emergence in embryos.
(J:307859)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:307859 Ng CE, et al., A Runx1 intronic enhancer marks hemogenic endothelial cells and hematopoietic stem cells. Stem Cells. 2010 Oct;28(10):1869-81 |
| All: |
1 reference(s) |
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Analysis Tools
