Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Runx1/Hspa1a-EGFP)523Mosa
Name:	transgene insertion 523, Motomi Osato
MGI ID:	MGI:6726471
Synonyms:	Runx1 +24 mCNE #523
Transgene:	Tg(Runx1/Hspa1a-EGFP)523Mosa  Location: unknown
Alliance:	Tg(Runx1/Hspa1a-EGFP)523Mosa page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Mutation details: The transgenic construct contains mouse Runx1 enhancer element sequence (eR1) also called Runx1 +24 mouse conserved noncoding element (mCNE) and the mouse Hspa1a (heat-shock protein 68) basal promoter sequence driving the expression of EGFP. Three distinct founder lines numbered 523, 540, and 542 were established. Although variation in the intensity of GFP fluorescence was observed, all three lines showed similar reporter gene expression patterns at sites of hematopoietic stem cell emergence in embryos. (J:307859)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:307859 Ng CE, et al., A Runx1 intronic enhancer marks hemogenic endothelial cells and hematopoietic stem cells. Stem Cells. 2010 Oct;28(10):1869-81
All:	1 reference(s)