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Gene Expression Data
Assay Details
Assay
Reference: J:249183 Saxon JG, et al., BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling. Dev Biol. 2017 Oct 1;430(1):113-128
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6726427
Gene symbol: Vcan
Gene name: versican
Antibody: anti-mouse versican (GAG-beta domain) (AB1033)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 9A: embryonic day 13.5; Bmp2tm1.1Mis/Bmp2+ (more )
Structure Level Pattern Image Note
TS21: atrioventricular endocardial cushion Present 9A
Specimen 9B: embryonic day 13.5; Bmp2tm1.1Mis/Bmp2tm1Brd, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: atrioventricular endocardial cushion Present 9B Reduced expression compared with the control.
Specimen 12A: postnatal day 5; Bmp2tm1.1Mis/Bmp2+ (more )
Structure Level Pattern Image Note
TS28: mitral valve Strong Regionally restricted 12A Intensely expressed in the spongiosa.
Specimen 12B: postnatal day 5; Bmp2tm1.1Mis/Bmp2tm1Brd, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: mitral valve Strong Regionally restricted 12B Loss of stratification and expansion of the spogiosa were seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory