Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Aldh1a1tm1(cre/ERT2)Awar
Name:	aldehyde dehydrogenase family 1, subfamily A1; targeted mutation 1, Rajeshwar Awatramani
MGI ID:	MGI:6726326
Synonyms:	Aldh1a1-CreERT2
Gene:	Aldh1a1  Location: Chr19:20470079-20620829 bp, + strand  Genetic Position: Chr19, 13.91 cM
Alliance:	Aldh1a1tm1(cre/ERT2)Awar page

Germline Transmission:	Earliest citation of germline transmission: J:266806
Parent Cell Line:	PRX-B6N (ES Cell)
Strain of Origin:	C57BL/6NTac

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Aldh1a1tm1(cre/ERT2)Awar expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Aldh1a1 (MGI:1353450)   Mutation details: By homologous recombination in ES cells, a CreERT2, a WPRE fragment, and bGH pA followed by FRT flanked neo cassette was inserted into the Aldh1a1 gene in-frame to the endogenous ATG. (J:266806)

Activity:	Tissue activity of this recombinase allele
Driver:	Aldh1a1 (mouse) Summary of all recombinase alleles driven by Aldh1a1. Alliance mouse Aldh1a1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aldh1a1 Mutation:	37 strains or lines available

Original:	J:266806 Poulin JF, et al., Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches. Nat Neurosci. 2018 Sep;21(9):1260-1271
All:	2 reference(s)