Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Cd8a-icre/ERT2,-GFP)#Daav
Name:	transgene insertion, Dario AA Vignali
MGI ID:	MGI:6726258
Synonyms:	E8ICreERT2.GFP
Transgene:	Tg(Cd8a-icre/ERT2,-GFP)#Daav  Location: unknown
Alliance:	Tg(Cd8a-icre/ERT2,-GFP)#Daav page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Tg(Cd8a-icre/ERT2,-GFP)#Daav expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Cd8a (MGI:88346)   Mutation details: The 1.6 kb core of the E8I Cd8 locus enhancer region was inserted in front of the Cd8a promoter, and iCreERT2 cDNA and an IRES-GFP-polyA cassette were inserted after the promoter to generate the transgene construct. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:299786)

Activity:	Tissue activity of this recombinase allele
Driver:	Cd8a (mouse) Summary of all recombinase alleles driven by Cd8a. Alliance mouse Cd8a gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:299786 Liu C, et al., Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity. Nat Immunol. 2020 Sep;21(9):1010-1021
All:	7 reference(s)